{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T07:01:54Z","timestamp":1777878114530,"version":"3.51.4"},"reference-count":36,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2011,5,5]],"date-time":"2011-05-05T00:00:00Z","timestamp":1304553600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Therapeutic Advances in Hematology"],"published-print":{"date-parts":[[2011,6]]},"abstract":"<jats:p>Background: The impact on health related quality of life (HRQoL) of rituximab maintenance (R-M) versus observation (OBS) after induction for treatment of follicular lymphoma (FL) is unclear.<\/jats:p>\n                  <jats:p>Methods: We reviewed the charts of 137 patients (53% female, 87% White, age 61.0\u2009\u00b1\u200912.4 years) who received either R-M ( n\u2009=\u200953) or OBS ( n\u2009=\u200984) after chemotherapy induction for newly diagnosed FL at community oncology practices within the US. Patients (65% with advanced disease; 48% with a high FLIPI score [3\u20135]) had completed \u22651 Patient Care Monitor HRQoL survey in the period following front-line therapy, and were excluded if they had progressed during front-line therapy.<\/jats:p>\n                  <jats:p>Results: Linear mixed models showed that postinduction, most symptoms were stable, with patients on R-M reporting HRQoL that was equal to that reported by OBS patients.<\/jats:p>\n                  <jats:p>Conclusions: Among R-M patients, receipt of rituximab was associated with improved psychological symptoms.<\/jats:p>","DOI":"10.1177\/2040620711407675","type":"journal-article","created":{"date-parts":[[2011,5,5]],"date-time":"2011-05-05T20:58:59Z","timestamp":1304629139000},"page":"129-139","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":10,"title":["Symptom burden and quality of life in patients with follicular lymphoma undergoing maintenance treatment with rituximab compared with observation"],"prefix":"10.1177","volume":"2","author":[{"given":"Mark S.","family":"Walker","sequence":"first","affiliation":[{"name":"ACORN Research, LLC, 6555 Quince, Suite 400, Memphis, TN 38119, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edward J.","family":"Stepanski","sequence":"additional","affiliation":[{"name":"ACORN Research, LLC, Memphis, TN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolina","family":"Reyes","sequence":"additional","affiliation":[{"name":"Genentech, South San Francisco, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sacha","family":"Satram-Hoang","sequence":"additional","affiliation":[{"name":"Genentech, South San Francisco, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arthur C.","family":"Houts","sequence":"additional","affiliation":[{"name":"ACORN Research, LLC, Memphis, TN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lee S.","family":"Schwartzberg","sequence":"additional","affiliation":[{"name":"West Clinic, Memphis, TN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2011,5,5]]},"reference":[{"key":"bibr1-2040620711407675","doi-asserted-by":"publisher","DOI":"10.3310\/hta13suppl2\/06"},{"key":"bibr2-2040620711407675","doi-asserted-by":"crossref","first-page":"1504","DOI":"10.1182\/blood-2006-01-013367","volume":"108","author":"Buske C.","year":"2006","journal-title":"Blood"},{"key":"bibr3-2040620711407675","doi-asserted-by":"publisher","DOI":"10.1002\/pon.1404"},{"key":"bibr4-2040620711407675","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0258(19971030)16:20<2349::AID-SIM667>3.0.CO;2-E"},{"key":"bibr5-2040620711407675","doi-asserted-by":"publisher","DOI":"10.1016\/j.spinee.2007.01.008"},{"key":"bibr6-2040620711407675","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2000.18.17.3135"},{"key":"bibr7-2040620711407675","doi-asserted-by":"publisher","DOI":"10.1080\/01621459.1999.10473858"},{"key":"bibr8-2040620711407675","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2005.03.1674"},{"key":"bibr9-2040620711407675","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2006-04-016725"},{"key":"bibr10-2040620711407675","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2005.07.009"},{"key":"bibr11-2040620711407675","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2008.18.1495"},{"key":"bibr12-2040620711407675","doi-asserted-by":"crossref","unstructured":"Ghielmini, M.E., Schmitz, S.H., Martinelli, G., Peccatori, F., Hess, U., Fey, M. et al. (2009) Long-term follow-up of patients with follicular lymphoma (FL) receiving single agent rituximab at two different schedules in study SAKK 35\/98. In: Proceedings of the Annual Meeting of the American Society of Clinical Oncology, 29 May\u20132 June, Orlando, FL.","DOI":"10.1200\/jco.2009.27.15_suppl.8512"},{"key":"bibr13-2040620711407675","doi-asserted-by":"publisher","DOI":"10.1007\/s12325-010-0069-7"},{"key":"bibr14-2040620711407675","doi-asserted-by":"publisher","DOI":"10.1053\/sonc.2002.30154"},{"key":"bibr15-2040620711407675","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2008.17.1561"},{"key":"bibr16-2040620711407675","volume-title":"Psychooncology","author":"Houts A.C.","year":"2009"},{"key":"bibr17-2040620711407675","doi-asserted-by":"publisher","DOI":"10.1016\/0197-2456(89)90005-6"},{"key":"bibr18-2040620711407675","doi-asserted-by":"publisher","DOI":"10.2165\/11201110-000000000-00000"},{"key":"bibr19-2040620711407675","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0258(20000715)19:13<1793::AID-SIM482>3.0.CO;2-Q"},{"key":"bibr20-2040620711407675","first-page":"20","volume":"22","author":"Maloney D.G.","year":"2008","journal-title":"Oncology (Williston Park)"},{"key":"bibr21-2040620711407675","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2007.13.5376"},{"key":"bibr22-2040620711407675","unstructured":"National Cancer Institute (2005) SEER cancer statistics review, 1975\u20132006. 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