{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T23:07:27Z","timestamp":1791328047171,"version":"4.3.1"},"reference-count":19,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2016,3,17]],"date-time":"2016-03-17T00:00:00Z","timestamp":1458172800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Therapeutic Advances in Hematology"],"published-print":{"date-parts":[[2016,6]]},"abstract":"<jats:p>Mogamulizumab (KW-0761) is a humanized immunoglobulin G1 (IgG1) monoclonal antibody (mAb) that targets CC chemokine receptor 4 (CCR4). It has shown promising therapeutic potential in phase I and II clinical trials and is currently being investigated for efficacy in treating cutaneous T-cell lymphoma (CTCL). We review the mechanism of action of mogamulizumab and its role in treating CTCL. We also discuss the results of major clinical trials.<\/jats:p>","DOI":"10.1177\/2040620716636541","type":"journal-article","created":{"date-parts":[[2016,3,17]],"date-time":"2016-03-17T21:59:59Z","timestamp":1458251999000},"page":"171-174","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":59,"title":["Mogamulizumab for the treatment of cutaneous T-cell lymphoma: recent advances and clinical potential"],"prefix":"10.1177","volume":"7","author":[{"given":"Madeleine","family":"Duvic","sequence":"first","affiliation":[{"name":"Department of Dermatology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Evans","sequence":"additional","affiliation":[{"name":"University of Utah School of Medicine, Salt Lake City, UT, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Casey","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Dermatology, The University of Texas MD Anderson Cancer Center, Pickens Tower, FCT11.6097, 1515 Holcombe Boulevard, Houston, TX 77030, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2016,3,17]]},"reference":[{"key":"bibr1-2040620716636541","doi-asserted-by":"publisher","DOI":"10.1007\/s12032-011-9955-3"},{"key":"bibr2-2040620716636541","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2014-09-600924"},{"key":"bibr3-2040620716636541","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-04-0983"},{"key":"bibr4-2040620716636541","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-04-0371"},{"key":"bibr5-2040620716636541","first-page":"3525","volume":"9","author":"Ishida T.","year":"2003","journal-title":"Clin Cancer Res"},{"key":"bibr6-2040620716636541","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-09-2697"},{"key":"bibr7-2040620716636541","doi-asserted-by":"publisher","DOI":"10.1007\/s00262-008-0632-0"},{"key":"bibr8-2040620716636541","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2011.237"},{"key":"bibr9-2040620716636541","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-14-0830"},{"key":"bibr10-2040620716636541","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2013.52.0924"},{"key":"bibr11-2040620716636541","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.12555"},{"key":"bibr12-2040620716636541","first-page":"605","volume":"25","author":"Ohshima K.","year":"2004","journal-title":"Int J Oncol"},{"key":"bibr13-2040620716636541","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M202069200"},{"key":"bibr14-2040620716636541","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M210665200"},{"key":"bibr15-2040620716636541","doi-asserted-by":"publisher","DOI":"10.1111\/1346-8138.12852"},{"key":"bibr16-2040620716636541","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2008.08612.x"},{"key":"bibr17-2040620716636541","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2002-05-1352"},{"key":"bibr18-2040620716636541","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2009.03771.x"},{"key":"bibr19-2040620716636541","first-page":"354","volume":"90","author":"Willemze R.","year":"1997","journal-title":"Blood"}],"container-title":["Therapeutic Advances in Hematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2040620716636541","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2040620716636541","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2040620716636541","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T23:13:36Z","timestamp":1777590816000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2040620716636541"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3,17]]},"references-count":19,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,6]]}},"alternative-id":["10.1177\/2040620716636541"],"URL":"https:\/\/doi.org\/10.1177\/2040620716636541","relation":{},"ISSN":["2040-6207","2040-6215"],"issn-type":[{"value":"2040-6207","type":"print"},{"value":"2040-6215","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,3,17]]}}}