{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T07:07:03Z","timestamp":1777878423262,"version":"3.51.4"},"reference-count":41,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Therapeutic Advances in Chronic Disease"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Medication adherence in Medicare-enrolled older adults with asthma and chronic obstructive pulmonary disease (COPD) before and during the coronavirus disease 2019 (COVID-19) pandemic is unknown.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>To evaluate medication adherence and determinants of high adherence before and during the COVID-19 pandemic in this population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>Retrospective cohort study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>The proportion of days covered (PDC) reflected medication adherence from January to July 2019 and from January to July 2020. Patients &lt;65\u2009years of age, with COPD or asthma alone, or with cystic fibrosis were excluded. Paired t tests were used to assess adherence changes. Logistic regression explored association of age, sex, diagnosis of depression, number of medications, medication-related problems, prescribers, pharmacies, controller medication classes, albuterol rescue inhaler fills, oral corticosteroid fills, and having a 90-day supply with high adherence (PDC\u2009\u2a7e\u200980%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>This analysis included 989 patients. In this cohort, 61.2% of patients received oral corticosteroids. Over 60% of patients had \u2a7e3 rescue fills in both 2019 and 2020. Medication adherence to controller medications significantly decreased for all controller medications ( p\u2009&lt;\u20090.001) in 2020. In 2019 and 2020, number of controller medication classes and having a 90-day supply were associated with high adherence ( p\u2009&lt;\u20090.001). In 2019, variables associated with high adherence also included number of medication-related problems and having \u2a7e3 albuterol rescue inhalers ( p\u2009&lt;\u20090.001).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Medication adherence to controllers significantly decreased during the pandemic among older adults with asthma and COPD. Patients with multiple controller classes and a 90-day supply were more likely to be highly adherent. A 90-day supply of medications should be used to facilitate access to medication during the pandemic. Healthcare professionals should assess medication adherence, resolve the barriers of adherence and medication-related problems to achieve desired clinical outcomes among older adults with both asthma and COPD.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/20406223231205796","type":"journal-article","created":{"date-parts":[[2023,10,9]],"date-time":"2023-10-09T06:34:45Z","timestamp":1696833285000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Medication adherence in Medicare-enrolled older adults with asthma and chronic obstructive pulmonary disease before and during COVID-19 pandemic"],"prefix":"10.1177","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4848-3000","authenticated-orcid":false,"given":"Ligang","family":"Liu","sequence":"first","affiliation":[{"name":"Institute of Therapeutic Innovations and Outcomes (ITIO), College of Pharmacy, The Ohio State University, Columbus, Ohio, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9601-9413","authenticated-orcid":false,"given":"Armando","family":"Silva Almod\u00f3var","sequence":"additional","affiliation":[{"name":"Institute of Therapeutic Innovations and Outcomes (ITIO), College of Pharmacy, The Ohio State University, Columbus, Ohio, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Milap C.","family":"Nahata","sequence":"additional","affiliation":[{"name":"Institute of Therapeutic Innovations and Outcomes (ITIO), College of Pharmacy, The Ohio State University, 500 West 12th Ave, Columbus, OH 43210, USA"},{"name":"College of Medicine, The Ohio State University, Columbus, Ohio, US"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,10,9]]},"reference":[{"key":"bibr1-20406223231205796","first-page":"1","volume":"427","author":"Murphy SL","year":"2021","journal-title":"NCHS Data Brief"},{"key":"bibr2-20406223231205796","doi-asserted-by":"publisher","DOI":"10.1016\/j.alit.2018.01.001"},{"key":"bibr3-20406223231205796","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/861926"},{"key":"bibr4-20406223231205796","doi-asserted-by":"publisher","DOI":"10.1513\/AnnalsATS.201508-554OC"},{"key":"bibr5-20406223231205796","doi-asserted-by":"publisher","DOI":"10.1016\/j.iac.2022.03.001"},{"key":"bibr6-20406223231205796","doi-asserted-by":"publisher","DOI":"10.1136\/bmjresp-2019-000470"},{"key":"bibr7-20406223231205796","doi-asserted-by":"publisher","DOI":"10.1080\/15412555.2021.1909549"},{"key":"bibr8-20406223231205796","doi-asserted-by":"publisher","DOI":"10.5415\/apallergy.2022.12.e21"},{"key":"bibr9-20406223231205796","unstructured":"2022 Global strategy for prevention, diagnosis and management of COPD: 2022 Report. 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