{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T07:19:10Z","timestamp":1777879150951,"version":"3.51.4"},"reference-count":11,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Therapeutic Advances in Endocrinology"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:p>Hyperparathyroidism (HPTH) is the third most common endocrine disorder. Hypovitaminosis D affects up to 40% of the general population and about a third of hyperparathyroid patients. Such a combination may alter the classic presentation of HPTH. This report presents a premenopausal female with long history of osteoporosis, normocalcemia, and hypovitaminosis D who was initially diagnosed as secondary HPTH. After restoring vitamin D to normal using parenteral loading doses, the patient developed persistent mild to moderate hypercalcemia with persistent parathormone elevation consistent with primary HPTH associated with hypercalciuria and complicated with nephrocalcinosis. Imaging confirmed a left upper parathyroid adenoma and fulfilling several indications for surgery, the patient was operated restoring normocalcemia that was maintained for several years of follow-up. Hypovitaminosis D is common and may mask expected hypercalcemia in patients with primary HPTH, thus delaying diagnosis and proper intervention. Reevaluating patients initially diagnosed as hypovitaminosis D and secondary HPTH may reveal a masked diagnosis of primary hyperparathyroidism.<\/jats:p>","DOI":"10.1177\/20420188231213208","type":"journal-article","created":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T07:20:46Z","timestamp":1700205646000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Hypovitaminosis D masking hypercalcemia in primary hyperparathyroidism: case report"],"prefix":"10.1177","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4074-3891","authenticated-orcid":false,"given":"Tamer Mohamed","family":"Elsherbiny","sequence":"first","affiliation":[{"name":"Endocrine division \u2013 Alexandria faculty of medicine, Alexandria University, Khartoum Square, Azarita, Alexandria 21521, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,11,17]]},"reference":[{"key":"bibr1-20420188231213208","doi-asserted-by":"publisher","DOI":"10.1038\/s41430-020-0558-y"},{"key":"bibr2-20420188231213208","doi-asserted-by":"publisher","DOI":"10.1038\/nrendo.2017.104"},{"key":"bibr3-20420188231213208","doi-asserted-by":"publisher","DOI":"10.1097\/MED.0b013e32834c3c7c"},{"key":"bibr4-20420188231213208","doi-asserted-by":"crossref","DOI":"10.1016\/j.endonu.2013.01.015","volume":"60","author":"Mart\u00ednez D\u00edaz-Guerra G","year":"2013","journal-title":"Endocrinol Nutr"},{"key":"bibr5-20420188231213208","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2014-1413"},{"key":"bibr6-20420188231213208","first-page":"1002","volume":"1","author":"Arrangoiz R","year":"2016","journal-title":"JSM Head Neck Cancer Cases Rev"},{"key":"bibr7-20420188231213208","doi-asserted-by":"publisher","DOI":"10.1016\/j.reuma.2011.06.001"},{"key":"bibr8-20420188231213208","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2013-3978"},{"key":"bibr9-20420188231213208","doi-asserted-by":"publisher","DOI":"10.1186\/s13256-016-0933-4"},{"key":"bibr10-20420188231213208","doi-asserted-by":"publisher","DOI":"10.1097\/TEN.0b013e31818fcd5f"},{"key":"bibr11-20420188231213208","doi-asserted-by":"publisher","DOI":"10.1258\/0004563041731619"}],"container-title":["Therapeutic Advances in Endocrinology and Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/20420188231213208","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/20420188231213208","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/20420188231213208","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T23:36:26Z","timestamp":1777592186000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/20420188231213208"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":11,"alternative-id":["10.1177\/20420188231213208"],"URL":"https:\/\/doi.org\/10.1177\/20420188231213208","relation":{},"ISSN":["2042-0188","2042-0196"],"issn-type":[{"value":"2042-0188","type":"print"},{"value":"2042-0196","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1]]},"article-number":"20420188231213208"}}