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It has been demonstrated to be useful in treating both thyroid eye disease (TED) and myasthenia gravis (MG), respectively. However, the effectiveness of RTX in concurrent TED and MG cases is unclear and not previously reported in the literature. In this study, we describe a 13-year-old girl who presented with a 10-year history of general MG and a 1-year history of Graves\u2019 disease, bilateral proptosis, eye motility restriction, and lagophthalmos. A comprehensive evaluation confirmed the diagnosis of concurrent TED and MG. Satisfactory effectiveness was observed after RTX treatment without side effects. Based on the described observations, we suggest that RTX should be further explored as a treatment option for patients with concurrent TED and MG.<\/jats:p>","DOI":"10.1177\/20420188251340137","type":"journal-article","created":{"date-parts":[[2025,5,28]],"date-time":"2025-05-28T05:03:18Z","timestamp":1748408598000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Rituximab for a rare pediatric case of concurrent thyroid eye disease and myasthenia gravis"],"prefix":"10.1177","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-2365-7609","authenticated-orcid":false,"given":"Haiyang","family":"Zhang","sequence":"first","affiliation":[{"name":"State Key Laboratory of Eye Health, Department of Ophthalmology, Shanghai Ninth People\u2019s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4623-8773","authenticated-orcid":false,"given":"Ting","family":"Lu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Eye Health, Department of Ophthalmology, Shanghai Ninth People\u2019s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3960-3840","authenticated-orcid":false,"given":"Yinwei","family":"Li","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Eye Health, Department of Ophthalmology, Shanghai Ninth People\u2019s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3155-2847","authenticated-orcid":false,"given":"Haixia","family":"Guan","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Guangdong Provincial People\u2019s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1692-3064","authenticated-orcid":false,"given":"Rebecca S.","family":"Bahn","sequence":"additional","affiliation":[{"name":"Consultant Emerita Division of Endocrinology, Professor of Medicine, Mayo Clinic College of Medicine, Mayo Clinic, Rochester, MN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8636-861X","authenticated-orcid":false,"given":"Huifang","family":"Zhou","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Eye Health, Department of Ophthalmology, Shanghai Ninth People\u2019s Hospital, Shanghai Jiao Tong University School of Medicine, No. 639, Zhizaoju Road, Huangpu District, Shanghai 200011, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,5,28]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.27118"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2015-213395"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-024-07368-0"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/joim.13524"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/WCO.0000000000000894"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.4103\/jnrp.jnrp_150_18"},{"issue":"9","key":"e_1_3_4_8_2","article-title":"Myasthenia gravis and its association with thyroid diseases","volume":"12","author":"Amin S","year":"2020","unstructured":"Amin S, Aung M, Gandhi FR, et al. 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