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Weight, body mass index, and other central obesity replacement indices (waist circumference, weight-adjusted waist index, waist-to-height ratio (WHtR), body roundness index (BRI)) and dietary nutrients intake (carbohydrate, sugars, fat, saturated fatty acids, monounsaturated fatty acids, polyunsaturated fatty acids (PUFAs), and cholesterol) were assessed. Propensity score matching (1:2) balanced covariates. Multivariable logistic regression and generalized additive models evaluated dose-response relationships.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      All central obesity indices showed significant positive associations with OAB (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001), with WHtR and BRI demonstrating the strongest effects (adjusted odds ratio (OR)\u2009=\u20092.04, 95% confidence interval: 1.80\u20132.30). Nonlinear relationships were observed, particularly for WHtR (degrees of freedom\u2009=\u20093.30\u20136.16). Dietary analysis revealed that OAB patients had significantly higher consumption of total energy, carbohydrates, and sugars (all\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.05), and higher sugar intake increased OAB risk (OR\u2009=\u20091.32,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.0016), while PUFAs were protective (OR\u2009=\u20090.79,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.0159).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Central obesity replacement indices, especially WHtR and BRI, strongly predict OAB risk. Dietary modifications, including reducing sugars and increasing PUFAs intake, may complement abdominal fat reduction for OAB prevention. These findings highlight the importance of combined weight management and dietary modifications for OAB prevention in high-risk populations.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/20420188261461860","type":"journal-article","created":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T04:46:48Z","timestamp":1783140408000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Association between dietary intake of fatty acids, central obesity, and OAB: insights from a prospective cohort for weight management and dietary prevention"],"prefix":"10.1177","volume":"17","author":[{"given":"Bo","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Urology, West China Hospital, Sichuan University, Chengdu, P.R. 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China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinze","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Urology, West China Hospital, Sichuan University, Chengdu, P.R. China"},{"name":"Department of Urology, People\u2019s Hospital of Deyang City, Affiliated to Chengdu University of Traditional Chinese Medicine, Deyang, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiyou","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Urology, West China Hospital, Sichuan University, Chengdu, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhe","family":"Yan","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu, P.R. 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