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Understanding the aetiology and epidemiology of drug-related problems is vital in developing methods to improve patient safety. In this perspective review, we discuss tools that are used to quantify exposure to \u2018high-risk\u2019 medications and their evaluation in residential aged-care settings. Drug withdrawal interventions are described as a potential way to reduce adverse drug events in RACFs. Multidisciplinary professional interventions, education programs and improved communication between health professionals have been shown to improve medication safety in RACFs. Technological advances and other administrative strategies may also improve resident safety. This perspective addresses issues in medication safety facing RACFs and methods to improve the safety of medicines for their residents.<\/jats:p>","DOI":"10.1177\/2042098610381418","type":"journal-article","created":{"date-parts":[[2010,11,3]],"date-time":"2010-11-03T16:07:10Z","timestamp":1288800430000},"page":"11-20","source":"Crossref","is-referenced-by-count":21,"title":["Medication safety in residential aged-care facilities: a perspective"],"prefix":"10.1177","volume":"1","author":[{"given":"Nicholas M.","family":"Wilson","sequence":"first","affiliation":[{"name":"Kolling Institute of Medical Research, Institute of Bone and Joint Research, Royal North Shore Hospital, St Leonards, NSW 2065 and Sydney Medical School, University of Sydney, Camperdown, NSW 2006, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lyn M.","family":"March","sequence":"additional","affiliation":[{"name":"Kolling Institute of Medical Research, Institute of Bone and Joint Research, Royal North Shore Hospital, St Leonards, NSW 2065 and Sydney Medical School, University of Sydney, Camperdown, NSW 2006, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip N.","family":"Sambrook","sequence":"additional","affiliation":[{"name":"Kolling Institute of Medical Research, Institute of Bone and Joint Research, Royal North Shore Hospital, St Leonards, NSW 2065 and Sydney Medical School, University of Sydney, Camperdown, NSW 2006, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah N.","family":"Hilmer","sequence":"additional","affiliation":[{"name":"Royal North Shore Hospital, St Leonards, NSW 2065, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2010,10,1]]},"reference":[{"key":"bibr1-2042098610381418","doi-asserted-by":"publisher","DOI":"10.1017\/S1041610201007487"},{"key":"bibr2-2042098610381418","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2005.53304.x"},{"key":"bibr3-2042098610381418","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.39520.671053.94"},{"key":"bibr4-2042098610381418","doi-asserted-by":"publisher","DOI":"10.4140\/TCP.n.2007.586"},{"key":"bibr5-2042098610381418","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.159.21.2553"},{"key":"bibr6-2042098610381418","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1991.00400090107019"},{"key":"bibr7-2042098610381418","doi-asserted-by":"publisher","DOI":"10.1080\/02813430600991980"},{"key":"bibr8-2042098610381418","first-page":"283","volume":"34","author":"Bollen C.","year":"2005","journal-title":"Aust Fam Physician"},{"key":"bibr9-2042098610381418","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.164.5.545"},{"key":"bibr10-2042098610381418","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1997.00440390083011"},{"key":"bibr11-2042098610381418","doi-asserted-by":"publisher","DOI":"10.1002\/pds.1797"},{"key":"bibr66-2042098610381418","unstructured":"Bureau of Health Professions (2010) State of Michigan Department of Community Health. 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