{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T07:20:51Z","timestamp":1777879251374,"version":"3.51.4"},"reference-count":10,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2018,2,6]],"date-time":"2018-02-06T00:00:00Z","timestamp":1517875200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Therapeutic Advances in Drug Safety"],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:p>An increased risk of bacterial resistance toward fluoroquinolones and the increased risk of disabling and serious adverse effects prompted the US Food and Drug Administration to recommend limiting fluoroquinolone use to the treatment of community-acquired pneumonia, skin and skin-structure infections, bacterial sinusitis, plague, chronic bronchitis exacerbations, and complicated intra-abdominal infections. We report a case of moxifloxacin-induced tinnitus in an older adult prescribed oral moxifloxacin 400 mg for 5 days for the treatment of acute diverticulitis, due to allergies to nonfluoroquinolone preferred agents. A thorough literature review provided few other reported incidents of this rare and serious adverse event.<\/jats:p>","DOI":"10.1177\/2042098618754483","type":"journal-article","created":{"date-parts":[[2018,2,6]],"date-time":"2018-02-06T23:49:05Z","timestamp":1517960945000},"page":"219-221","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Moxifloxacin-induced tinnitus in an older adult"],"prefix":"10.1177","volume":"9","author":[{"given":"Amber","family":"Onoh","sequence":"first","affiliation":[{"name":"University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, CO, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3271-7407","authenticated-orcid":false,"given":"Sunny A.","family":"Linnebur","sequence":"additional","affiliation":[{"name":"University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, CO, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danielle R.","family":"Fixen","sequence":"additional","affiliation":[{"name":"University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, 12850 E. Montview Blvd, Mail Stop C-238, V20-2127, Aurora, CO 80045, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2018,2,6]]},"reference":[{"key":"bibr1-2042098618754483","volume-title":"Avelox (moxifloxacin) package insert","author":"Merck &amp; Co., Inc","year":"2016"},{"key":"bibr2-2042098618754483","unstructured":"Food and Drug Administration. FDA updates warning for fluoroquinolone antibiotics, https:\/\/www.fda.gov\/Drugs\/DrugSafety\/ucm511530.htm (2016, accessed 24 August 2017)."},{"key":"bibr3-2042098618754483","doi-asserted-by":"publisher","DOI":"10.1089\/sur.2009.9930"},{"key":"bibr4-2042098618754483","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.311.6999.232b"},{"key":"bibr5-2042098618754483","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.1981.154"},{"key":"bibr6-2042098618754483","doi-asserted-by":"publisher","DOI":"10.3390\/ph3051286"},{"key":"bibr7-2042098618754483","doi-asserted-by":"publisher","DOI":"10.7874\/kja.2013.17.1.23"},{"key":"bibr8-2042098618754483","doi-asserted-by":"publisher","DOI":"10.2165\/00002018-199309020-00006"},{"key":"bibr9-2042098618754483","doi-asserted-by":"publisher","DOI":"10.1097\/FTD.0b013e3181951ed9"},{"key":"bibr10-2042098618754483","first-page":"79","volume":"34","author":"Sheppard A","year":"2014","journal-title":"Acta Otorhinolaryngol Ital"}],"container-title":["Therapeutic Advances in Drug Safety"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2042098618754483","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2042098618754483","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2042098618754483","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T23:38:44Z","timestamp":1777592324000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2042098618754483"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2,6]]},"references-count":10,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,4]]}},"alternative-id":["10.1177\/2042098618754483"],"URL":"https:\/\/doi.org\/10.1177\/2042098618754483","relation":{},"ISSN":["2042-0986","2042-0994"],"issn-type":[{"value":"2042-0986","type":"print"},{"value":"2042-0994","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,2,6]]}}}