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Raynaud\u2019s phenomenon (RP), a vasospastic syndrome and an important feature of different connective tissue diseases, is not an expected finding in AS patients. This article reports the development of secukinumab-related RP in a 35-year-old female patient with AS. Treatment with secukinumab was continued and RP was treated with low-dose aspirin and a calcium-channel blocker.<\/jats:p>","DOI":"10.1177\/2042098620905976","type":"journal-article","created":{"date-parts":[[2020,2,22]],"date-time":"2020-02-22T04:39:36Z","timestamp":1582346376000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Secukinumab-induced Raynaud\u2019s phenomenon: first report in the literature"],"prefix":"10.1177","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8270-640X","authenticated-orcid":false,"given":"Senol","family":"Kobak","sequence":"first","affiliation":[{"name":"Department of Rheumatology, LIV Hospital, Istinye University Faculty of Medicine, Canan sokak No: 5, Ulus\/Istanbul, 34340, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,2,22]]},"reference":[{"key":"bibr1-2042098620905976","doi-asserted-by":"publisher","DOI":"10.1007\/s11926-019-0838-5"},{"key":"bibr2-2042098620905976","doi-asserted-by":"publisher","DOI":"10.1016\/j.berh.2018.12.002"},{"key":"bibr3-2042098620905976","doi-asserted-by":"publisher","DOI":"10.1007\/s40265-019-01075-3"},{"key":"bibr4-2042098620905976","doi-asserted-by":"publisher","DOI":"10.1080\/14712598.2019.1554053"},{"key":"bibr5-2042098620905976","doi-asserted-by":"publisher","DOI":"10.2147\/TCRM.S100091"},{"key":"bibr6-2042098620905976","doi-asserted-by":"publisher","DOI":"10.1016\/j.berh.2016.04.001"},{"key":"bibr7-2042098620905976","doi-asserted-by":"publisher","DOI":"10.1038\/nrrheum.2012.96"},{"key":"bibr8-2042098620905976","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1507638"},{"key":"bibr9-2042098620905976","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2018.04.007"},{"key":"bibr10-2042098620905976","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehs263"},{"key":"bibr11-2042098620905976","doi-asserted-by":"publisher","DOI":"10.1111\/bcp.12912"},{"key":"bibr12-2042098620905976","doi-asserted-by":"publisher","DOI":"10.1016\/j.therap.2017.01.008"},{"key":"bibr13-2042098620905976","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.72.3.466"},{"key":"bibr14-2042098620905976","doi-asserted-by":"publisher","DOI":"10.1007\/s00228-011-1084-6"},{"key":"bibr15-2042098620905976","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2012.02124.x"},{"key":"bibr16-2042098620905976","volume":"31","author":"Garcia-Porrua C","year":"2004","journal-title":"J Rheumatol"},{"key":"bibr17-2042098620905976","doi-asserted-by":"publisher","DOI":"10.1097\/RHU.0b013e3181639aaa"},{"key":"bibr18-2042098620905976","doi-asserted-by":"publisher","DOI":"10.1111\/j.1368-5031.2005.00566a.x"},{"key":"bibr19-2042098620905976","doi-asserted-by":"publisher","DOI":"10.1007\/s100670170031"},{"key":"bibr20-2042098620905976","doi-asserted-by":"publisher","DOI":"10.1159\/000072453"},{"key":"bibr21-2042098620905976","first-page":"216","volume":"17","author":"Freudiger H","year":"1988","journal-title":"Vasa"},{"key":"bibr22-2042098620905976","first-page":"408","volume":"31","author":"Mohokum M","year":"2012","journal-title":"Int Angiol"},{"key":"bibr23-2042098620905976","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2012.09215.x"},{"key":"bibr24-2042098620905976","doi-asserted-by":"publisher","DOI":"10.1016\/j.therap.2017.01.008"},{"key":"bibr25-2042098620905976","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.56.652.106"}],"container-title":["Therapeutic Advances in Drug Safety"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2042098620905976","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2042098620905976","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2042098620905976","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T23:39:27Z","timestamp":1777592367000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2042098620905976"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1]]},"references-count":25,"alternative-id":["10.1177\/2042098620905976"],"URL":"https:\/\/doi.org\/10.1177\/2042098620905976","relation":{},"ISSN":["2042-0986","2042-0994"],"issn-type":[{"value":"2042-0986","type":"print"},{"value":"2042-0994","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1]]},"article-number":"2042098620905976"}}