{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T07:27:23Z","timestamp":1777879643736,"version":"3.51.4"},"reference-count":14,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2013,5,9]],"date-time":"2013-05-09T00:00:00Z","timestamp":1368057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Therapeutic Advances in Psychopharmacology"],"published-print":{"date-parts":[[2013,10]]},"abstract":"<jats:p>Clozapine (Denzapine) is a treatment for resistant schizophrenia. Among the serious but rare side effects of clozapine are agranulocytosis and priapism. We hereby present the case of a 30-year-old man with a diagnosis of schizophrenia who has spent nearly 12 years of his adult life on various psychiatric in-patient units including open wards, secure units, psychiatric intensive care units and rehab wards. Diagnosed at the age of 15, he only responded to clozapine at the age of 18. Whilst being on clozapine he developed priapism in June 2010 and needed emergency surgical treatment in the form of surgical decompression. He again responded only to clozapine and fortunately he did not redevelop priapism; however, he was readmitted in February 2011 due to relapse, and he remained resistant to other antipsychotics. He was rechallenged with clozapine and recovered, but unfortunately redeveloped priapism which required emergency surgical and medical intervention (goserline acetate and tinzaperin injection). In order to relieve the recurrent priapism, he agreed to continue clozapine and goserline acetate injection. This decision was made by the patient in a compos mentis state. As far as we are aware, this is the first time goserline acetate has been reported as a successful treatment for clozapine-induced priapism.<\/jats:p>","DOI":"10.1177\/2045125313488132","type":"journal-article","created":{"date-parts":[[2013,5,9]],"date-time":"2013-05-09T20:57:08Z","timestamp":1368133028000},"page":"298-300","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Treatment of clozapine-induced priapism by goserline acetate injection"],"prefix":"10.1177","volume":"3","author":[{"given":"Gursharan Lal","family":"Kashyap","sequence":"first","affiliation":[{"name":"SEPT, Weller Wing, Ampthill Road, Bedford, Bedfordshire, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jitendra","family":"Nayar","sequence":"additional","affiliation":[{"name":"SEPT, Weller Wing, Ampthill Road, Bedford, Bedfordshire, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adnan","family":"Bashier","sequence":"additional","affiliation":[{"name":"SEPT, Weller Wing, Ampthill Road, Bedford, Bedfordshire, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soosamma","family":"Varghese","sequence":"additional","affiliation":[{"name":"SEPT, Weller Wing, Ampthill Road, Bedford, Bedfordshire, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2013,5,9]]},"reference":[{"key":"bibr1-2045125313488132","doi-asserted-by":"publisher","DOI":"10.1097\/00004850-199703000-00008"},{"key":"bibr2-2045125313488132","first-page":"145","volume":"154","author":"Bertholon F.","year":"1996","journal-title":"Ann Med Psychol"},{"key":"bibr3-2045125313488132","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v62n0510"},{"key":"bibr4-2045125313488132","doi-asserted-by":"publisher","DOI":"10.1097\/00004714-199808000-00023"},{"key":"bibr5-2045125313488132","unstructured":"Dougherty C., Richard A., Carey M. (2012) Priapism in emergency medicine. emedicine.medscape.com\/article\/777603-overview (accessed on 16 November 2012)."},{"key":"bibr6-2045125313488132","doi-asserted-by":"publisher","DOI":"10.1046\/j.1464-410X.2002.02825.x"},{"key":"bibr7-2045125313488132","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2005.07.042"},{"key":"bibr8-2045125313488132","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-60761-916-1"},{"key":"bibr9-2045125313488132","unstructured":"Netherlands Pharmacovigilance Center Lareb (2006) Citalopram and priaprism. https:\/\/www.lareb.nl\/LarebCorporateWebsite\/media\/publicaties\/kwb_2006_4_citalopr.pdf (accessed on 16 November 2012)."},{"key":"bibr10-2045125313488132","first-page":"59","volume":"135","author":"Reif R.","year":"1993","journal-title":"Acta Univ Palacki Olomuc Fac Med"},{"key":"bibr11-2045125313488132","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)37166-5"},{"key":"bibr12-2045125313488132","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.158.12.2087-a"},{"key":"bibr13-2045125313488132","doi-asserted-by":"publisher","DOI":"10.1097\/YIC.0b013e3282f1c1ef"},{"key":"bibr14-2045125313488132","first-page":"1675","volume":"29","author":"Tsukagoshi S.","year":"2002","journal-title":"Gan To Kagaku Ryoho"}],"container-title":["Therapeutic Advances in Psychopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2045125313488132","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2045125313488132","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2045125313488132","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T23:49:33Z","timestamp":1777592973000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2045125313488132"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,5,9]]},"references-count":14,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2013,10]]}},"alternative-id":["10.1177\/2045125313488132"],"URL":"https:\/\/doi.org\/10.1177\/2045125313488132","relation":{},"ISSN":["2045-1253","2045-1261"],"issn-type":[{"value":"2045-1253","type":"print"},{"value":"2045-1261","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,5,9]]}}}