{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T04:45:39Z","timestamp":1793681139030,"version":"4.5.1"},"reference-count":36,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2018,10,10]],"date-time":"2018-10-10T00:00:00Z","timestamp":1539129600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Eur J Prev Cardiolog"],"published-print":{"date-parts":[[2019,2]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Cardiac rehabilitation improves health-related quality of life (HRQoL) and reduces hospitalizations in patients with heart failure, but international uptake of cardiac rehabilitation for heart failure remains low.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design and methods<\/jats:title>\n                    <jats:p>The aim of this multicentre randomized trial was to compare the REACH-HF (Rehabilitation EnAblement in CHronicHeart Failure) intervention, a facilitated self-care and home-based cardiac rehabilitation programme to usual care for adults with heart failure with reduced ejection fraction (HFrEF). The study primary hypothesis was that the addition of the REACH-HF intervention to usual care would improve disease-specific HRQoL (Minnesota Living with Heart Failure questionnaire (MLHFQ)) at 12 months compared with usual care alone.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The study recruited 216 participants, predominantly men (78%), with an average age of 70 years and mean left ventricular ejection fraction of 34%. Overall, 185 (86%) participants provided data for the primary outcome. At 12 months, there was a significant and clinically meaningful between-group difference in the MLHFQ score of \u20135.7 points (95% confidence interval \u201310.6 to \u20130.7) in favour of the REACH-HF intervention group ( p\u2009=\u20090.025). With the exception of patient self-care ( p\u2009&lt;\u20090.001) there was no significant difference in other secondary outcomes, including clinical events ( p\u2009&gt;\u20090.05) at follow-up compared with usual care. The mean cost of the REACH-HF intervention was \u00a3418 per participant.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The novel REACH-HF home-based facilitated intervention for HFrEF was clinically superior in disease-specific HRQoL at 12 months and offers an affordable alternative to traditional centre-based programmes to address current low cardiac rehabilitation uptake rates for heart failure.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/2047487318806358","type":"journal-article","created":{"date-parts":[[2018,10,10]],"date-time":"2018-10-10T19:01:41Z","timestamp":1539198101000},"page":"262-272","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":147,"title":["The effects and costs of home-based rehabilitation for heart failure with reduced ejection fraction: The REACH-HF multicentre randomized controlled trial"],"prefix":"10.1093","volume":"26","author":[{"given":"Hasnain M","family":"Dalal","sequence":"first","affiliation":[{"name":"Institute of Health Research, University of Exeter Medical School, Exeter, UK"},{"name":"Royal Cornwall Hospitals NHS Trust, Truro, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rod S","family":"Taylor","sequence":"additional","affiliation":[{"name":"Institute of Health Research, University of Exeter Medical School, Exeter, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kate","family":"Jolly","sequence":"additional","affiliation":[{"name":"Institute of Applied Health Research, University of Birmingham, Birmingham, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Russell C","family":"Davis","sequence":"additional","affiliation":[{"name":"Cardiology Department, Sandwell & West Birmingham Hospitals NHS Trust, Birmingham, 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