{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T07:40:36Z","timestamp":1767858036679,"version":"3.49.0"},"reference-count":28,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T00:00:00Z","timestamp":1554076800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Eur J Prev Cardiolog"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:sec><jats:title>Aims<\/jats:title><jats:p> Overall, 40% of patients with atrial fibrillation are asymptomatic. The usefulness and cost-effectiveness of atrial fibrillation screening programmes are debated. We evaluated whether an atrial fibrillation screening programme with a handheld electrocardiogram (ECG) machine in a population-wide cohort has a high screening yield and is cost-effective. <\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p> We used a Markov-model based modelling analysis on 1000 hypothetical individuals who matched the Belgian Heart Rhythm Week screening programme. Subgroup analyses of subjects \u226565 and \u226575 years old were performed. Screening was performed with one-lead ECG handheld machine Omron\u00ae HeartScan HCG-801. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p> In both overall population and subgroups, the use of the screening procedure diagnosed a consistently higher number of diagnosed atrial fibrillation than not screening. In the base-case scenario, the screening procedure resulted in 106.6 more atrial fibrillation patient-years, resulting in three fewer strokes, 10 more life years and five more quality-adjusted life years (QALYs). The number needed-to-screen (NNS) to avoid one stroke was 361. In subjects \u226565 years old, we found 80.8 more atrial fibrillation patient-years, resulting in three fewer strokes, four more life-years and five more QALYs. The NNS to avoid one stroke was 354. Similar results were obtained in subjects \u226575 years old, with a NNS to avoid one stroke of 371. In the overall population, the incremental cost-effectiveness ratio for any gained QALY showed that the screening procedure was cost-effective in all groups. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p> In a population-wide screening cohort, the use of a handheld ECG machine to identify subjects with newly diagnosed atrial fibrillation was cost-effective in the general population, as well as in subjects \u226565 and subjects \u226575 years old. <\/jats:p><\/jats:sec>","DOI":"10.1177\/2047487319839184","type":"journal-article","created":{"date-parts":[[2019,4,2]],"date-time":"2019-04-02T01:01:27Z","timestamp":1554166887000},"page":"964-972","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":25,"title":["Cost-effectiveness and screening performance of ECG handheld machine in a population screening programme: The Belgian Heart Rhythm Week screening programme"],"prefix":"10.1093","volume":"26","author":[{"given":"Marco","family":"Proietti","sequence":"first","affiliation":[{"name":"Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessio","family":"Farcomeni","sequence":"additional","affiliation":[{"name":"Department of Public Health and Infectious Diseases, Sapienza-University of Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Goethals","sequence":"additional","affiliation":[{"name":"Clinique St. Jean, Brussels, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christophe","family":"Scavee","sequence":"additional","affiliation":[{"name":"Cliniques Universitaires St. Luc, Brussels, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johan","family":"Vijgen","sequence":"additional","affiliation":[{"name":"Jessa Ziekenhuis, Hasselt, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivan","family":"Blankoff","sequence":"additional","affiliation":[{"name":"CHU Charleroi, Lodelinsart, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yves","family":"Vandekerckhove","sequence":"additional","affiliation":[{"name":"Algemene Ziekenhuis St. Jan, Brugges, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gregory YH","family":"Lip","sequence":"additional","affiliation":[{"name":"Liverpool Centre for Cardiovascular Science, University of Liverpool and Liverpool Heart & Chest Hospital, UK"},{"name":"Aalborg Thrombosis Research Unit, Department of Clinical Medicine, Aalborg University, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georges H","family":"Mairesse","sequence":"additional","affiliation":[{"name":"Cliniques du Sud-Luxembourg, Arlon, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"on behalf of Belgian Heart Rhythm Week Investigators","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2019,4,1]]},"reference":[{"key":"bibr1-2047487319839184","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euw295"},{"key":"bibr2-2047487319839184","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2015.05.011"},{"key":"bibr3-2047487319839184","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1313600"},{"key":"bibr4-2047487319839184","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(15)70027-X"},{"key":"bibr5-2047487319839184","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.39280.660567.55"},{"key":"bibr6-2047487319839184","doi-asserted-by":"publisher","DOI":"10.1160\/TH13-02-0165"},{"key":"bibr7-2047487319839184","first-page":"1779","volume":"18","author":"Proietti 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