{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:16:10Z","timestamp":1787019370773,"version":"build-2736575974"},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"18","license":[{"start":{"date-parts":[[2019,6,20]],"date-time":"2019-06-20T00:00:00Z","timestamp":1560988800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Eur J Prev Cardiolog"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>In the rehabilitation of cardiovascular disease patients a correct determination of the endurance-type exercise intensity is important to generate health benefits and preserve medical safety. It remains to be assessed whether the guideline-based exercise intensity domains are internally consistent and agree with physiological responses to exercise in cardiovascular disease patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A total of 272 cardiovascular disease patients without pacemaker executed a maximal cardiopulmonary exercise test on bike (peak respiratory gas exchange ratio &gt;1.09), to assess peak heart rate (HR\n                      <jats:sub>peak<\/jats:sub>\n                      ), oxygen uptake (VO\n                      <jats:sub>2peak<\/jats:sub>\n                      ) and cycling power output (W\n                      <jats:sub>peak<\/jats:sub>\n                      ). The first and second ventilatory threshold (VT1 and VT2, respectively) was determined and extrapolated to %VO\n                      <jats:sub>2peak<\/jats:sub>\n                      , %HR\n                      <jats:sub>peak<\/jats:sub>\n                      , %heart rate reserve (%HRR) and %W\n                      <jats:sub>peak<\/jats:sub>\n                      for comparison with guideline-based exercise intensity domains.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      VT1 was noted at 62\u2009\u00b1\u200910% VO\n                      <jats:sub>2peak<\/jats:sub>\n                      , 75\u2009\u00b1\u200910% HR\n                      <jats:sub>peak<\/jats:sub>\n                      , 42\u2009\u00b1\u200914% HRR and 47\u2009\u00b1\u200911% W\n                      <jats:sub>peak<\/jats:sub>\n                      , corresponding to the high intensity exercise domain (for %VO\n                      <jats:sub>2peak<\/jats:sub>\n                      and %HR\n                      <jats:sub>peak<\/jats:sub>\n                      ) or low intensity exercise domain (for %W\n                      <jats:sub>peak<\/jats:sub>\n                      and %HRR). VT2 was noted at 84\u2009\u00b1\u20099% VO\n                      <jats:sub>2peak<\/jats:sub>\n                      , 88\u2009\u00b1\u20098% HR\n                      <jats:sub>peak<\/jats:sub>\n                      , 74\u2009\u00b1\u200915% HRR and 76\u2009\u00b1\u200911% W\n                      <jats:sub>peak<\/jats:sub>\n                      , corresponding to the high intensity exercise domain (for %HRR and %W\n                      <jats:sub>peak<\/jats:sub>\n                      ) or very hard exercise domain (for %HR\n                      <jats:sub>peak<\/jats:sub>\n                      and %VO\n                      <jats:sub>2peak<\/jats:sub>\n                      ). At best (when using %W\n                      <jats:sub>peak<\/jats:sub>\n                      ) in only 63% and 72% of all patients VT1 and VT2, respectively, corresponded to the same guideline-based exercise intensity domain, but this dropped to about 48% and 52% at worst (when using %HRR and %HR\n                      <jats:sub>peak<\/jats:sub>\n                      , respectively). In particular, the patient\u2019s VO\n                      <jats:sub>2peak<\/jats:sub>\n                      related to differently elicited guideline-based exercise intensity domains ( P\u2009&lt;\u20090.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The guideline-based exercise intensity domains for cardiovascular disease patients seem inconsistent, thus reiterating the need for adjustment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/2047487319859450","type":"journal-article","created":{"date-parts":[[2019,6,20]],"date-time":"2019-06-20T12:11:19Z","timestamp":1561032679000},"page":"1921-1928","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":82,"title":["Exercise training intensity determination in cardiovascular rehabilitation: Should the guidelines be reconsidered?"],"prefix":"10.1093","volume":"26","author":[{"given":"Dominique","family":"Hansen","sequence":"first","affiliation":[{"name":"REVAL \u2013 Rehabilitation Research Center, Hasselt University, Belgium"},{"name":"Jessa Hospital, Heart Center Hasselt, Belgium"},{"name":"BIOMED \u2013 Biomedical Research Center, Hasselt University, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kim","family":"Bonn\u00e9","sequence":"additional","affiliation":[{"name":"Jessa Hospital, Heart Center Hasselt, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toon","family":"Alders","sequence":"additional","affiliation":[{"name":"Jessa Hospital, Heart Center Hasselt, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann","family":"Hermans","sequence":"additional","affiliation":[{"name":"Jessa Hospital, Heart Center Hasselt, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katrien","family":"Copermans","sequence":"additional","affiliation":[{"name":"Jessa Hospital, Heart Center Hasselt, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans","family":"Swinnen","sequence":"additional","affiliation":[{"name":"Jessa Hospital, Heart Center Hasselt, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Maris","sequence":"additional","affiliation":[{"name":"REVAL \u2013 Rehabilitation Research Center, Hasselt University, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Jansegers","sequence":"additional","affiliation":[{"name":"REVAL \u2013 Rehabilitation Research Center, Hasselt University, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wout","family":"Mathijs","sequence":"additional","affiliation":[{"name":"REVAL \u2013 Rehabilitation Research Center, Hasselt University, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Haenen","sequence":"additional","affiliation":[{"name":"REVAL \u2013 Rehabilitation Research Center, Hasselt University, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johan","family":"Vaes","sequence":"additional","affiliation":[{"name":"Jessa Hospital, Heart Center Hasselt, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuela","family":"Govaerts","sequence":"additional","affiliation":[{"name":"Jessa Hospital, Heart Center Hasselt, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veerle","family":"Reenaers","sequence":"additional","affiliation":[{"name":"Jessa Hospital, Heart Center Hasselt, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ines","family":"Frederix","sequence":"additional","affiliation":[{"name":"Jessa Hospital, Heart Center Hasselt, Belgium"},{"name":"BIOMED \u2013 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