{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T04:25:25Z","timestamp":1793507125407,"version":"4.5.0"},"reference-count":82,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2019,10,16]],"date-time":"2019-10-16T00:00:00Z","timestamp":1571184000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"},{"start":{"date-parts":[[2019,10,16]],"date-time":"2019-10-16T00:00:00Z","timestamp":1571184000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,7,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Cancer and cardiovascular diseases are the leading causes of death in high-income countries. Cardiovascular complications can be found in cancer patients, being the result of so-called \u2018cardio-toxicity\u2019. Therefore, it becomes essential to thoroughly investigate the origin of cardiac damage and the strategy to prevent it or to reverse the negative remodelling associated with cardiotoxicity. In this review the beneficial effects of physical exercise in cancer patients were analysed, particularly to prevent cardio-toxicity before its clinical manifestation. According to the relevance of exercise, we suggest strategies for exercise prescription with a tailored approach in these patients. In conclusion, physical exercise seems to be a promising and effective treatment for cancer patients during and after therapy and seems to counteract the negative effects induced by drugs on the cardiovascular system. Exercise prescription should be tailored according to patient\u2019s individual characteristics, to the drugs administered, to the personal history, and to his\/her response to exercise, taking into account that different types of training can be prescribed according also to the patient\u2019s choice. A cardiological evaluation including exercise testing is essential for an appropriate prescription of exercise in these patients.<\/jats:p>","DOI":"10.1177\/2047487319874900","type":"journal-article","created":{"date-parts":[[2019,10,7]],"date-time":"2019-10-07T04:00:30Z","timestamp":1570420830000},"page":"725-735","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":78,"title":["The benefits of exercise in cancer patients and the criteria for exercise prescription in cardio-oncology"],"prefix":"10.1093","volume":"28","author":[{"given":"Flavio","family":"D\u2019Ascenzi","sequence":"first","affiliation":[{"name":"Department of Medical Biotechnologies, University of Siena, Italy"},{"name":"Department of Medicine, University of Pittsburgh, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Anselmi","sequence":"additional","affiliation":[{"name":"Department of Medical Biotechnologies, University of Siena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caterina","family":"Fiorentini","sequence":"additional","affiliation":[{"name":"Department of Medical Biotechnologies, University of Siena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberta","family":"Mannucci","sequence":"additional","affiliation":[{"name":"Institute for Health, University of Pittsburgh Medical Center, C. Terme (Siena), Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Bonifazi","sequence":"additional","affiliation":[{"name":"Department of Medicine, Science, and Neurosciences, University of Siena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio","family":"Mondillo","sequence":"additional","affiliation":[{"name":"Department of Medical Biotechnologies, University of Siena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2019,10,16]]},"reference":[{"key":"2021120107035853400_zwaa184-B1","doi-asserted-by":"crossref","first-page":"394","DOI":"10.3322\/caac.21492","article-title":"Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"68","author":"Bray","year":"2018","journal-title":"CA Cancer J 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