{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T03:56:49Z","timestamp":1777435009075,"version":"3.51.4"},"reference-count":9,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T00:00:00Z","timestamp":1359676800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Acta Radiologica Short Reports"],"published-print":{"date-parts":[[2013,2]]},"abstract":"<jats:p>The overall prognosis for patients with \u00df-thalassemia has improved considerably during the past decades mainly due to regular blood transfusions, improvements in chelation therapy, and enhanced surveillance with imaging studies examining iron overload and other clinical complications. However, the prolonged survival of these patients leads to the development of other health problems including degenerative diseases such as arthropathies, which require further attention since they have a significant impact on the quality of life. In the current case report, we present a 45-year-old white man with \u00df-thalassemia complaining of non-traumatic pain and restriction in the range of motion of both knees. Magnetic resonance imaging (MRI) revealed a tear in the medial meniscus of the left knee as well as iron deposits in both knees. Histological findings confirmed the presence of hemosiderin in both joints. To our knowledge, this is the first reported case of macroscopically documented iron deposits in the knee joints of a patient with \u00df-thalassemia using MRI.<\/jats:p>","DOI":"10.1177\/2047981613477401","type":"journal-article","created":{"date-parts":[[2013,5,3]],"date-time":"2013-05-03T14:56:14Z","timestamp":1367592974000},"page":"1-5","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Iron deposits in the knee joints of a thalassemic patient"],"prefix":"10.1177","volume":"2","author":[{"given":"Charalambos P","family":"Economides","sequence":"first","affiliation":[{"name":"Cyprus Institute of Biomedical Sciences (CIBS), Nicosia, Cyprus;"},{"name":"Agios Therissos MRI Diagnostic Center, Department of MRI, Nicosia, Cyprus;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elpidoforos S","family":"Soteriades","sequence":"additional","affiliation":[{"name":"Cyprus Institute of Biomedical Sciences (CIBS), Nicosia, Cyprus;"},{"name":"Harvard School of Public Health, Department of Environmental Health, Environmental and Occupational Medicine and Epidemiology (EOME), Boston, MA, USA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michalis","family":"Hadjigavriel","sequence":"additional","affiliation":[{"name":"Limassol General Hospital, Department of Internal Medicine, Limassol, Cyprus;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ioannis","family":"Seimenis","sequence":"additional","affiliation":[{"name":"Democritus University of Thrace, Medical School, Laboratory of Medical Physics, Alexandroupoli, Greece;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Apostolos","family":"Karantanas","sequence":"additional","affiliation":[{"name":"University of Crete, Department of Medical Imaging, Heraklion-Crete, Crete"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2013,2,1]]},"reference":[{"key":"bibr1-2047981613477401","doi-asserted-by":"publisher","DOI":"10.1159\/000089475"},{"key":"bibr2-2047981613477401","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.175.6.1751561"},{"key":"bibr3-2047981613477401","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2004.05202.x"},{"key":"bibr4-2047981613477401","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2011.03.077"},{"key":"bibr5-2047981613477401","doi-asserted-by":"publisher","DOI":"10.4103\/0971-3026.50839"},{"key":"bibr6-2047981613477401","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(94)92585-2"},{"key":"bibr7-2047981613477401","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.183.4.1830989"},{"key":"bibr8-2047981613477401","author":"Noetzli LJ","year":"2011","journal-title":"Am J Hematol"},{"key":"bibr9-2047981613477401","doi-asserted-by":"publisher","DOI":"10.1259\/bjr\/53300812"}],"container-title":["Acta Radiologica Short Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2047981613477401","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2047981613477401","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2047981613477401","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:55:18Z","timestamp":1777377318000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2047981613477401"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,2]]},"references-count":9,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,2]]}},"alternative-id":["10.1177\/2047981613477401"],"URL":"https:\/\/doi.org\/10.1177\/2047981613477401","relation":{},"ISSN":["2047-9816"],"issn-type":[{"value":"2047-9816","type":"print"}],"subject":[],"published":{"date-parts":[[2013,2]]}}}