{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T10:37:23Z","timestamp":1777545443912,"version":"3.51.4"},"reference-count":28,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["JRSM Cardiovascular Disease"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Left ventricular free wall rupture (LVFWR) is a rare but severe complication of acute myocardial infarction (AMI). During the era of pre-thrombolysis, autopsies revealed an incidence of approximately 8%.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>The objective of this retrospective study was to analyze the current incidence of LVFWR and to identify predictors by comparing the AMI-cohort with LVFWR to those without. The control group involved a random selection of one in every ten patients who presented with acute myocardial infarction between 2005 and 2014.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Result<\/jats:title>\n                    <jats:p>A total of 5143 patients with AMI were treated at the Central Hospital, Bad Berka (71% men, median age 68\u2009years). Out of these, seven patients with LVFWR were identified with an overall incidence of 0.14%. Clinically, LVFWR patients presented late to admission since symptom onset (median 24\u2009h vs. 6.1\u2009h; p\u2009&lt;\u20090.0001), were more likely in cardiogenic shock (28.6% vs. 3.2%; p\u2009=\u20090.02) and were usually accompanied by emergency physicians (71.4% vs. 20.7%; p\u2009=\u20090.006). Higher troponin T (median 8.6 vs. 0.5\u2009ng\/ml; p\u2009&lt;\u20090.0002), higher CRP (median 50 vs. 0.5\u2009mg\/l; p\u2009=\u20090.05) as well as a lower hematocrit-values (0.33 vs. 0.42; p\u2009=\u20090.04) were observed. All LVFWR patients were operated (100% vs. 1.6%; p\u2009&lt;\u20090.001). The patients had lower rates of beta-blocker treatment (57.1% vs. 95.8%; p\u2009=\u20090.003). The 30-day mortality was significantly higher (42.9% vs. 6.8%; p\u2009=\u20090.01).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Compared to the thrombolytic era, the current incidence of LVFWR with AMI, who reach the hospital alive, is significantly lower. However, 30-day mortality continues to be high.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/2048004019896692","type":"journal-article","created":{"date-parts":[[2019,12,18]],"date-time":"2019-12-18T00:29:26Z","timestamp":1576628966000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":11,"title":["Left ventricular free wall rupture in myocardial infarction: A retrospective analysis from a single tertiary center"],"prefix":"10.1177","volume":"8","author":[{"given":"Swaroop","family":"Varghese","sequence":"first","affiliation":[{"name":"Department of Cardiology, Harzklinikum, Wernigerode, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6412-5935","authenticated-orcid":false,"given":"Marc-Alexander","family":"Ohlow","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Zentralklinik, Bad Berka, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,12,17]]},"reference":[{"key":"bibr1-2048004019896692","first-page":"246","volume":"43","author":"Exadaktylos NI","year":"2002","journal-title":"Hellenic J Cardiol"},{"key":"bibr2-2048004019896692","unstructured":"Willens FA, Dry TJ. 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