{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T10:34:29Z","timestamp":1777545269897,"version":"3.51.4"},"reference-count":73,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["JRSM Cardiovascular Disease"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:p>The practice of interventional cardiology has changed dramatically over the last four decades since Andreas Gruentzig carried out the first balloon angioplasty. The obvious technological improvements in stent design and interventional techniques have facilitated the routine treatment of a higher risk cohort of patients, including those with complex coronary artery disease and poor left ventricular function, and more often in the setting of cardiogenic shock (CS) complicating acute myocardial infarction (AMI). The use of mechanical cardiac support (MCS) in these settings has been the subject of intense interest, particularly over the past decade . A number of commercially available devices now add to the interventional cardiologist\u2019s armamentarium when faced with the critically unwell or high-risk patient in the cardiac catheter laboratory. The theoretical advantage of such devices in these settings is clear- an increase in cardiac output and hence mean arterial pressure, with variable effects on coronary blood flow. In doing so, they have the potential to prevent the downward cascade of ischaemia and hypoperfusion, but there is a paucity of evidence to support their routine use in any patient subset, even those presenting with cardiogenic shock. This review will discuss the use and haemodynamic effect of MCS devices during percutaneous coronary intervention (PCI), and also examine the clinical evidence for their use in patients with cardiogenic shock, and those undergoing \u2018high risk\u2019 PCI<\/jats:p>","DOI":"10.1177\/20480040211014064","type":"journal-article","created":{"date-parts":[[2021,10,20]],"date-time":"2021-10-20T15:28:22Z","timestamp":1634743702000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["The role of mechanical support devices during percutaneous coronary intervention"],"prefix":"10.1177","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4079-2578","authenticated-orcid":false,"given":"Ritesh","family":"Kanyal","sequence":"first","affiliation":[{"name":"King\u2019s College Hospital NHS Foundation Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan","family":"Byrne","sequence":"additional","affiliation":[{"name":"King\u2019s College Hospital NHS Foundation Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,10,19]]},"reference":[{"key":"bibr1-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2016.10.023"},{"key":"bibr2-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1007\/s00392-017-1192-0"},{"key":"bibr3-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1111\/joic.12080"},{"key":"bibr4-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1016\/j.ehj.2003.07.002"},{"key":"bibr5-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.116.004337"},{"key":"bibr6-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2014.07.030"},{"key":"bibr7-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2016.02.046"},{"key":"bibr8-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2015.10.017"},{"key":"bibr9-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2015-308562"},{"key":"bibr10-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.24421"},{"key":"bibr11-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2004.03.060"},{"key":"bibr12-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.114.001258"},{"key":"bibr13-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2013.11.023"},{"key":"bibr14-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1097\/01.MAT.0000159381.97773.9B"},{"key":"bibr15-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2013.01.575"},{"key":"bibr16-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1093\/icvts\/ivs017"},{"key":"bibr17-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1007\/s40119-019-00152-8"},{"key":"bibr18-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.118.007707"},{"key":"bibr19-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.117.005870"},{"key":"bibr20-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.22263"},{"key":"bibr21-20480040211014064","unstructured":"Briceno N, Khan SQ, Clapp B, et\u00a0al. 32 Does \u2018real-world\u2019 mechanical circulatory support match randomised controlled trials? The United Kingdom impella (Ukpella) registry.\n                      Heart\n                      2020; 106 (Suppl 2):A1 \u2013 A118. 1\u20132."},{"key":"bibr22-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1177\/2048872618805486"},{"key":"bibr23-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.0254"},{"key":"bibr24-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1111\/joic.12571"},{"key":"bibr25-20480040211014064","doi-asserted-by":"crossref","unstructured":"Anderson M, Morris DL, Tang D, et\u00a0al.  Outcomes of patients with right ventricular failure requiring short-term hemodynamic support with the Impella RP device. https:\/\/doi.org\/10.1016\/j.healun.2018.08.001","DOI":"10.1016\/j.healun.2018.08.001"},{"key":"bibr26-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.116.025290"},{"key":"bibr27-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.117.006670"},{"key":"bibr28-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.23465"},{"key":"bibr29-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehi161"},{"key":"bibr30-20480040211014064","unstructured":"NHS. Evidence review: mechanical assist devices for circulatory support (destination therapy) in people with advanced heart failure 1 2017;1\u201363."},{"key":"bibr31-20480040211014064","doi-asserted-by":"publisher","DOI":"10.21037\/jtd.2019.03.29"},{"key":"bibr32-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2018.11.038"},{"key":"bibr33-20480040211014064","doi-asserted-by":"crossref","DOI":"10.1016\/j.jacc.2015.02.043","volume":"65","author":"Rihal CS","year":"2015","journal-title":"J Am Coll Cardiol"},{"key":"bibr34-20480040211014064","doi-asserted-by":"crossref","unstructured":"England TN. Complicated by cardiogenic shock. 1999; 341:625\u2013634.","DOI":"10.1056\/NEJM199908263410901"},{"key":"bibr35-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1808788"},{"key":"bibr36-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2015.12.074"},{"key":"bibr37-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2016.12.005"},{"key":"bibr38-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1007\/s11239-005-0938-0"},{"key":"bibr39-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2006.05.031"},{"key":"bibr40-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.05.065"},{"key":"bibr41-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2016.10.022"},{"key":"bibr42-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/14.1.71"},{"key":"bibr43-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1097\/SHK.0b013e31824a67af"},{"key":"bibr44-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1208410"},{"key":"bibr45-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.118.038201"},{"key":"bibr46-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(03)00400-5"},{"key":"bibr47-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1067\/mhj.2001.115295"},{"key":"bibr48-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2015.0569"},{"key":"bibr49-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehn602"},{"key":"bibr50-20480040211014064","first-page":"362","volume":"127","author":"Anderson JL.","year":"2013","journal-title":"Circulation"},{"key":"bibr51-20480040211014064","first-page":"119","volume":"39","author":"Ibanez B","year":"2018","journal-title":"Eur Heart J. ESC Scientific Document Group"},{"key":"bibr52-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2016.11.037"},{"key":"bibr53-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2018.03.008"},{"key":"bibr54-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.118.036614"},{"key":"bibr55-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1007\/s00392-019-01458-2"},{"key":"bibr56-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrc.2015.05.022"},{"key":"bibr57-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-016-4536-8"},{"key":"bibr58-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.116.022061"},{"key":"bibr59-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2009.09.018"},{"key":"bibr60-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2008.11.005"},{"key":"bibr61-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.112.132209"},{"key":"bibr62-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2011.1280"},{"key":"bibr63-20480040211014064","doi-asserted-by":"publisher","DOI":"10.4244\/EIJY14M09_10"},{"key":"bibr64-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.112.098194"},{"key":"bibr65-20480040211014064","doi-asserted-by":"publisher","DOI":"10.4244\/EIJ-D-18-01126"},{"key":"bibr66-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.119.044007"},{"key":"bibr67-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(93)90089-J"},{"key":"bibr68-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(91)90606-A"},{"key":"bibr69-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0304(199810)45:2<115::AID-CCD3>3.0.CO;2-F"},{"key":"bibr70-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehy394"},{"key":"bibr71-20480040211014064","first-page":"9","volume":"9","author":"Lindseth RO.","year":"2002","journal-title":"Card Interv Today"},{"key":"bibr72-20480040211014064","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1002\/ccd.28329","volume":"94","author":"Baran DA","year":"2019","journal-title":"Catheter Cardiovasc Interv"},{"key":"bibr73-20480040211014064","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2019.04.019"}],"container-title":["JRSM Cardiovascular Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/20480040211014064","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/20480040211014064","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/20480040211014064","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T17:32:48Z","timestamp":1777397568000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/20480040211014064"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":73,"alternative-id":["10.1177\/20480040211014064"],"URL":"https:\/\/doi.org\/10.1177\/20480040211014064","relation":{},"ISSN":["2048-0040","2048-0040"],"issn-type":[{"value":"2048-0040","type":"print"},{"value":"2048-0040","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1]]},"article-number":"20480040211014064"}}