{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T23:36:09Z","timestamp":1792798569066,"version":"4.5.0"},"reference-count":41,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2017,6,2]],"date-time":"2017-06-02T00:00:00Z","timestamp":1496361600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Heart Journal: Acute Cardiovascular Care"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:sec><jats:title>Background:<\/jats:title><jats:p> Increased left ventricular afterload during peripheral venoarterial-extracorporeal membrane oxygenation (VA-ECMO) support frequently causes hydrostatic pulmonary oedema. Because physiological studies demonstrated left ventricular afterload decrease during VA-ECMO assistance combined with the intra-aortic balloon pump (IABP), we progressively changed our standard practice systematically to associate an IABP with VA-ECMO. This study aimed to evaluate IABP efficacy in preventing pulmonary oedema in VA-ECMO-assisted patients. <\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p> A retrospective single-centre study. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p> Among 259 VA-ECMO patients included, 104 received IABP. Weinberg radiological score-assessed pulmonary oedema was significantly lower in IABP<jats:sup>+<\/jats:sup> than IABP<jats:sup>\u2013<\/jats:sup> patients at all times after ECMO implantation. This protection against pulmonary oedema persisted when death and switching to central ECMO were used as competing risks (subhazard ratio 0.49, 95% confidence interval (CI) 0.33\u20130.75; P&lt;0.001). Multivariable analysis retained IABP as being independently associated with a lower risk of radiological pulmonary oedema (odds ratio (OR) 0.4, 95% CI 0.2\u20130.7; P=0.001) and a trend towards lower mortality (OR 0.54, 95% CI 0.29\u20131.01; P=0.06). Finally, the time on ECMO free from mechanical ventilation increased in IABP<jats:sup>+<\/jats:sup> patients (2.2\u00b14.3 vs. 0.7\u00b12.0 days; P=0.0003). Less frequent pulmonary oedema and more days off mechanical ventilation were also confirmed in 126 highly comparable IABP<jats:sup>+<\/jats:sup> and IABP<jats:sup>\u2013<\/jats:sup> patients, propensity score matched for receiving an IABP. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions:<\/jats:title><jats:p> Associating an IABP with peripheral VA-ECMO was independently associated with a lower frequency of hydrostatic pulmonary oedema and more days off mechanical ventilation under ECMO. <\/jats:p><\/jats:sec>","DOI":"10.1177\/2048872617711169","type":"journal-article","created":{"date-parts":[[2017,6,2]],"date-time":"2017-06-02T15:03:12Z","timestamp":1496415792000},"page":"62-69","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":119,"title":["Intra-aortic balloon pump protects against hydrostatic pulmonary oedema during peripheral venoarterial-extracorporeal membrane oxygenation"],"prefix":"10.1093","volume":"7","author":[{"given":"Nicolas","family":"Br\u00e9chot","sequence":"first","affiliation":[{"name":"Medical-Surgical ICU, H\u00f4pital Piti\u00e9\u2013Salp\u00eatri\u00e8re, France"},{"name":"INSERM U1050, Centre Interdisciplinaire de Recherche en Biologie, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Demondion","sequence":"additional","affiliation":[{"name":"Cardiac Surgery Department, H\u00f4pital Piti\u00e9\u2013Salp\u00eatri\u00e8re, France"},{"name":"Sorbonne University, Institute of Cardiometabolism and Nutrition, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Santi","sequence":"additional","affiliation":[{"name":"Cardiac Surgery Department, H\u00f4pital Piti\u00e9\u2013Salp\u00eatri\u00e8re, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillaume","family":"Lebreton","sequence":"additional","affiliation":[{"name":"Cardiac 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