{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T20:32:59Z","timestamp":1779395579325,"version":"3.53.1"},"reference-count":19,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"},{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2020,12,1]]},"abstract":"<jats:sec>\n                  <jats:title>Background:<\/jats:title>\n                  <jats:p>Emerging evidence suggests that coronary intensive care units are evolving into intensive care environments with an increasing burden of non-cardiovascular illness, but previous studies have been limited to older populations or single center experiences.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods:<\/jats:title>\n                  <jats:p>Canadian national health-care data was used to identify all patients \u226518 years admitted to dedicated coronary intensive care units (2005\u20132015) and admissions were categorized as primary cardiac or non-cardiac. The outcomes of interest included longitudinal trends in admission diagnoses, critical care therapies, and all-cause in-hospital mortality.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results:<\/jats:title>\n                  <jats:p>Among the 373,992 patients admitted to a coronary intensive care unit, minimal changes in the proportion of patients admitted with a primary cardiac (88.2% to 86.9%; p&amp;lt;0.001) and non-cardiac diagnoses (11.8% to 13.1%; p&amp;lt;0.001) were observed. Among cardiac admissions, a temporal increase in the proportion of ST-segment elevation myocardial infarction (19.4% to 24.1%, p&amp;lt;0.001), non-ST-segment elevation myocardial infarction (14.6% to 16.2%, p&amp;lt;0.001), heart failure (7.3% to 8.4%, p&amp;lt;0.001), shock (4.9% to 5.7%, p&amp;lt;0.001), and decline in unstable angina (4.9% to 4.0%, p&amp;lt;0.001) and stable coronary diseases (21.3% to 12.4%, p&amp;lt;0.001) was observed. The proportion of patients requiring critical care therapies (57.8% to 63.5%, p&amp;lt;0.001) including mechanical ventilation (9.6% to 13.1%, p&amp;lt;0.001) increased. In-hospital mortality rates for patients with primary cardiac (4.9% to 4.4%; adjusted odds ratio 0.71, 95% confidence interval 0.63\u20130.79) and non-cardiac (17.8% to 16.1%; adjusted odds ratio 0.84, 0.73\u20130.97) declined; results were consistent when stratified by academic vs community hospital, and by the presence of on-site percutaneous coronary intervention.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion:<\/jats:title>\n                  <jats:p>In a national dataset we observed a changing case-mix among patients admitted to a coronary intensive care unit, though the proportion of patients with a primary cardiac diagnosis remained stable. There was an increase in clinical acuity highlighted by critical care therapies, but in-hospital mortality rates for both primary cardiac and non-cardiac conditions declined across all hospitals. Our findings confirm the changing coronary intensive care unit case-mix and have implications for future coronary intensive care unit training and staffing.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1177\/2048872619883400","type":"journal-article","created":{"date-parts":[[2019,10,30]],"date-time":"2019-10-30T14:47:33Z","timestamp":1572446853000},"page":"923-930","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["National trends in coronary intensive care unit admissions, resource utilization, and outcomes"],"prefix":"10.1093","volume":"9","author":[{"given":"Sarah","family":"Woolridge","sequence":"first","affiliation":[{"name":"Division of Cardiology, University of Alberta, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wendimagegn","family":"Alemayehu","sequence":"additional","affiliation":[{"name":"Canadian Vigour Center, University of Alberta, 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