{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T07:33:06Z","timestamp":1777879986681,"version":"3.51.4"},"reference-count":32,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Therapeutic Advances in Infection"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Patients with substance use disorders (SUDs) and severe bacterial infections requiring prolonged antibiotic therapy represent a significant challenge to providers due to complexity of care coordination required to ensure safe and effective treatment. Our institution developed a patient-centered multidisciplinary discharge planning conference, OPTIONS-DC, to address this challenge.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We conducted a retrospective review to evaluates parameters between patients who received an OPTIONS-DC and those who did not.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>We identified 73 patients receiving an OPTIONS-DC and 100 who did not. More patients with an OPTIONS-DC were &lt;\u200940\u2009years of age (76.7% versus 61.0%, OR\u2009=\u20092.3, 95% CI\u2009=\u20091.1\u20134.7, p\u2009=\u20090.02), had positive HCV antibody testing (58.9% versus 41.0%, OR\u2009=\u20092.1, 95% CI\u2009=\u20091.1\u20133.8, p\u2009=\u20090.02), injection drug use (93.2% versus 79.0%, OR\u2009=\u20093.6 95% CI\u2009=\u20091.3\u201310.1, p\u2009=\u20090.01), used methamphetamines (84.9% versus 72.0%, OR\u2009=\u20092.2, 95% CI\u2009=\u20091.0\u20134.8, p\u2009=\u20090.04), and started inpatient SUD treatment (80.8% versus 63%, OR\u2009=\u20092.5, 95% CI\u2009=\u20091.2\u20135.0, p\u2009=\u20090.04) compared with those without a conference. The OPTIONS-DC group was more likely to be diagnosed with bacteremia (74.0% versus 57.0%, OR\u2009=\u20092.1, 95% CI\u2009=\u20091.1\u20134.1, p\u2009=\u20090.02), endocarditis (39.7% versus21.0%, OR\u2009=\u20092.5, 95% CI\u2009=\u20091.3\u20134.9, p\u2009=\u20090.03), vertebral osteomyelitis (45.2% versus 15.0%, OR\u2009=\u20094.7, 95% CI\u2009=\u20092.3\u20139.6, p\u2009&lt;\u20090.01), and epidural abscess (35.6% versus 10.0%, OR\u2009=\u20095.0, 95% CI\u2009=\u20092.2\u201311.2, p\u2009&lt;\u20090.01) and require 4\u2009weeks or more of antibiotic treatment (97.3% versus 51.1%, OR\u2009=\u200934.1, 95% CI\u2009=\u20097.9\u2013146.7, p\u2009=\u20090.01). Patients with an OPTIONS-DC were also more likely to be admitted between 2019 and 2020 than between 2018 and 2019 (OR\u2009=\u20094.1, 95% CI\u2009=\u20092.1\u20137.9, p\u2009&lt;\u20090.01).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Patients with an OPTIONS-DC tended to have more complicated infections and longer courses of antibiotic treatment. While further research on outcomes is needed, patients receiving an OPTIONS-DC were able to successfully complete antibiotic courses across a variety of settings.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/20499361221117974","type":"journal-article","created":{"date-parts":[[2022,8,17]],"date-time":"2022-08-17T03:18:40Z","timestamp":1660706320000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Description and outcomes of patients with substance use disorder with serious bacterial infections who had a multidisciplinary care conference"],"prefix":"10.1177","volume":"9","author":[{"given":"Michael","family":"Conte","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases, School of Medicine, Oregon Health & Science University, Portland, OR, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brent","family":"Schneider","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, School of Medicine, Oregon Health & Science University, Portland, OR, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3209-4489","authenticated-orcid":false,"given":"Cara D.","family":"Varley","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, School of Medicine, Oregon Health & Science University, Portland, OR, USA"},{"name":"School of Public Health, Oregon Health & Science University\u2013Portland State University, Portland, OR, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amber C.","family":"Streifel","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Oregon Health & Science University, Portland, OR, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8192-8019","authenticated-orcid":false,"given":"Monica K.","family":"Sikka","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, School of Medicine, Oregon Health & Science University, Portland, OR 97239-3098, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,8,17]]},"reference":[{"key":"bibr1-20499361221117974","unstructured":"Centers for Disease Control and Prevention. 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