{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T19:12:40Z","timestamp":1779909160148,"version":"3.53.1"},"reference-count":20,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["K23AI166277"],"award-info":[{"award-number":["K23AI166277"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Therapeutic Advances in Infection"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>With recent increases in syphilis, there is growing interest in expanding screening; however, treatment rates have historically been low.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>This study examines demographic and clinical factors that may contribute to non-completion of syphilis treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>This is a retrospective comparative cohort study of all patients with syphilis from January through November 2018 at an urban, tertiary care hospital.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Demographics and clinical information were extracted from the electronic medical record. Descriptive statistics and odds ratios (ORs) were calculated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Of 171 patients with syphilis, 89 (52.0%) completed treatment. Patients ages 40\u201349 were least likely to complete treatment (OR 0.14; 95% CI 0.03\u20130.72, p = 0.02) compared to those ages 18\u201324. Non-heterosexual patients were significantly more likely to complete treatment (OR 3.60; 95% CI 1.13\u201311.49, p = 0.03) compared to heterosexual patients. Patients diagnosed in the emergency department completed treatment at the lowest rate.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>A major gap in syphilis treatment still exists, which must be addressed to achieve optimal impact from syphilis screening programs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/20499361241265941","type":"journal-article","created":{"date-parts":[[2024,7,31]],"date-time":"2024-07-31T02:58:23Z","timestamp":1722394703000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Risk factors for treatment non-completion among patients with syphilis"],"prefix":"10.1177","volume":"11","author":[{"given":"Abigail","family":"Clarkson-During","sequence":"first","affiliation":[{"name":"Section of Emergency Medicine, The University of Chicago, Chicago, IL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ellen","family":"Almirol","sequence":"additional","affiliation":[{"name":"Section of Infectious Diseases and Global Health, The University of Chicago, Chicago, IL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dylan","family":"Eller","sequence":"additional","affiliation":[{"name":"Section of Infectious Diseases and Global Health, The University of Chicago, Chicago, IL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8557-4465","authenticated-orcid":false,"given":"Aniruddha","family":"Hazra","sequence":"additional","affiliation":[{"name":"Section of Infectious Diseases and Global Health, The University of Chicago, Chicago, IL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7374-1323","authenticated-orcid":false,"given":"Kimberly A.","family":"Stanford","sequence":"additional","affiliation":[{"name":"Section of Emergency Medicine, The University of Chicago, 5841 S. Maryland Avenue, MC 5068, Chicago, IL 60637, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,7,30]]},"reference":[{"key":"bibr1-20499361241265941","author":"Centers for Disease Control and Prevention","year":"2024","journal-title":"Sexually transmitted infections surveillance 2022"},{"key":"bibr2-20499361241265941","unstructured":"Centers for Disease Control and Prevention. Sexually transmitted infections treatment guidelines, 2021. https:\/\/www.cdc.gov\/std\/treatment-guidelines\/syphilis.htm (2024, accessed 16 March 2024)."},{"key":"bibr3-20499361241265941","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6922a1"},{"key":"bibr4-20499361241265941","doi-asserted-by":"publisher","DOI":"10.1097\/OLQ.0000000000001775"},{"key":"bibr5-20499361241265941","doi-asserted-by":"publisher","DOI":"10.1097\/OLQ.0000000000001770"},{"key":"bibr6-20499361241265941","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-147-8-200710160-00010"},{"key":"bibr7-20499361241265941","doi-asserted-by":"publisher","DOI":"10.1891\/LGBTQ-2021-0039"},{"key":"bibr8-20499361241265941","doi-asserted-by":"publisher","DOI":"10.1097\/OLQ.0000000000001311"},{"key":"bibr9-20499361241265941","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-020-05520-7"},{"key":"bibr10-20499361241265941","doi-asserted-by":"publisher","DOI":"10.3390\/healthcare10061059"},{"key":"bibr11-20499361241265941","doi-asserted-by":"publisher","DOI":"10.1071\/SH09117"},{"key":"bibr12-20499361241265941","doi-asserted-by":"publisher","DOI":"10.1016\/j.jemermed.2012.08.022"},{"key":"bibr13-20499361241265941","volume":"15","author":"Iyeke LO","year":"2023","journal-title":"Cureus"},{"key":"bibr14-20499361241265941","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2019.6282"},{"key":"bibr15-20499361241265941","doi-asserted-by":"publisher","DOI":"10.3389\/frph.2023.1082429"},{"key":"bibr16-20499361241265941","volume":"93","author":"Gliddon HD","year":"2017","journal-title":"Sex Transm Infect"},{"key":"bibr17-20499361241265941","doi-asserted-by":"publisher","DOI":"10.1097\/ACM.0000000000005182"},{"key":"bibr18-20499361241265941","unstructured":"National Center for HIV, Viral Hepatitis, STD, and TB Prevention. PrEP for HIV prevention in the U.S., https:\/\/www.cdc.gov\/nchhstp\/newsroom\/fact-sheets\/hiv\/PrEP-for-hiv-prevention-in-the-US-factsheet.html (2021, accessed 15 July 2022)."},{"key":"bibr19-20499361241265941","doi-asserted-by":"publisher","DOI":"10.1186\/s12913-017-2824-9"},{"key":"bibr20-20499361241265941","doi-asserted-by":"publisher","DOI":"10.1097\/PHH.0000000000000448"}],"container-title":["Therapeutic Advances in Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/20499361241265941","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/20499361241265941","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/20499361241265941","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:29Z","timestamp":1777593629000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/20499361241265941"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":20,"alternative-id":["10.1177\/20499361241265941"],"URL":"https:\/\/doi.org\/10.1177\/20499361241265941","relation":{},"ISSN":["2049-9361","2049-937X"],"issn-type":[{"value":"2049-9361","type":"print"},{"value":"2049-937X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1]]},"article-number":"20499361241265941"}}