{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T07:35:03Z","timestamp":1777880103468,"version":"3.51.4"},"reference-count":17,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Therapeutic Advances in Infection"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:p>\n                    <jats:italic toggle=\"yes\">Micrococcus luteus<\/jats:italic>\n                    (\n                    <jats:italic toggle=\"yes\">M. luteus<\/jats:italic>\n                    ) is a Gram-positive microorganism that typically dwells in environments such as soil, water, and human skin, hence, entitling it as a contaminant organism. However, there are instances where\n                    <jats:italic toggle=\"yes\">M. luteus<\/jats:italic>\n                    affects immunocompromised patients, such as in infective endocarditis and septic arthritis, but typically among immunocompromised patients. However, an evolutionary change has been observed in the infectious capability of this organism especially with reports emerging on its instance among immunocompetent population. A 68-year-old female presented to the emergency medicine department with complaints of persistent fever and neck soreness. Patient\u2019s blood culture reports were positive for\n                    <jats:italic toggle=\"yes\">M. luteus<\/jats:italic>\n                    and owing to her history of undergoing prosthetic valve replacement. A preliminary diagnosis of prosthetic valve infective endocarditis was made. However, since\n                    <jats:italic toggle=\"yes\">M. luteus<\/jats:italic>\n                    was a typical skin contaminant, and its infective etiology was limited toward immunocompromised patients, blood cultures were repeated for confirmation. Repeat blood cultures ascertained the suspicion of\n                    <jats:italic toggle=\"yes\">M. luteus<\/jats:italic>\n                    ; hence, treatment with intravenous vancomycin was initiated. Patient was discharged after 8\u2009week of treatment following complete eradication of infective markers and symptomatic improvement. Here, we report the novel occurrence of prosthetic valve infective endocarditis, by a typically contaminant organism, in an immunocompetent individual, hence, raising concerns on the evolutionary changes in the organism,\n                    <jats:italic toggle=\"yes\">M. luteus<\/jats:italic>\n                    .\n                  <\/jats:p>","DOI":"10.1177\/20499361251403054","type":"journal-article","created":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T06:58:27Z","timestamp":1766041107000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["<i>Micrococcus luteus<\/i>\n                    -induced prosthetic valve infective endocarditis in an immunocompetent patient: a case report from India"],"prefix":"10.1177","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-7751-2533","authenticated-orcid":false,"given":"Ritvik","family":"Sajan","sequence":"first","affiliation":[{"name":"Department of Pharmacy Practice Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, AIMS Health Sciences Campus, Kochi, Kerala, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3741-064X","authenticated-orcid":false,"given":"Sreekrishnan Trikkur","family":"Parasuraman","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Amrita Institute of Medical Sciences and Research Centre, Ernakulam, Kochi, Kerala, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1787-054X","authenticated-orcid":false,"given":"Akhil","family":"Arun","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Practice, Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, AIMS Ponekkara P.O, Kochi, Kerala 682041, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,12,17]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.778886"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2017.01.017"},{"key":"e_1_3_4_4_2","unstructured":"Rajput FA Zeltser R. Aortic valve replacement. In: StatPearls. Treasure Island FL: StatPearls Publishing http:\/\/www.ncbi.nlm.nih.gov\/books\/NBK537136\/ (2025 accessed 22 March 2025)."},{"issue":"2","key":"e_1_3_4_5_2","article-title":"Aortic valve surgery: marked increases in volume and significant decreases in mechanical valve use\u2014an analysis of 41,227 patients over 5 years from the Society for Cardiothoracic Surgery in Great Britain and Ireland National database","volume":"142","author":"Dunning J","year":"2011","unstructured":"Dunning J, Gao H, Chambers J, et al. Aortic valve surgery: marked increases in volume and significant decreases in mechanical valve use\u2014an analysis of 41,227 patients over 5 years from the Society for Cardiothoracic Surgery in Great Britain and Ireland National database. J Thoracic Cardiovascular Surg 2011; 142(2): 776\u2013782.E3.","journal-title":"J Thoracic Cardiovascular Surg"},{"key":"e_1_3_4_6_2","unstructured":"Complications of prosthetic heart valves | Current Cardiology Reports https:\/\/link.springer.com\/article\/10.1007\/s11886-004-0007-x (accessed 22 March 2025)."},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(10)63816-7"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.3390\/pathogens13121039"},{"key":"e_1_3_4_9_2","unstructured":"Risk factors for early onset prosthetic valve endocarditis: a case\u2013control study - Journal of Hospital Infection https:\/\/www.journalofhospitalinfection.com\/article\/S0195-6701(18)30377-3\/abstract (2018 accessed 22 March 2025)."},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.idcr.2019.e00657"},{"key":"e_1_3_4_11_2","unstructured":"The Pediatric Infectious Disease Journal https:\/\/journals.lww.com\/pidj\/fulltext\/2021\/07000\/first_report_of_micrococcus_luteus_native_valve.33.aspx (2021 accessed 7 March 2025)."},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.33073\/pjm-2021-030"},{"key":"e_1_3_4_13_2","article-title":"Advances in medicine and positive natural selection: prosthetic valve endocarditis due to biofilm producer","volume":"20","author":"Rodriguez-Nava G","year":"2020","unstructured":"Rodriguez-Nava G, Mohamed A, Yanez-Bello MA, et al. Advances in medicine and positive natural selection: prosthetic valve endocarditis due to biofilm producer Micrococcus luteus. IDCases 2020; 20: e00743.","journal-title":"Micrococcus luteus. IDCases"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciad271"},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000296"},{"key":"e_1_3_4_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2023.07.531"},{"key":"e_1_3_4_17_2","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms11061614"},{"key":"e_1_3_4_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2018.03.030"}],"container-title":["Therapeutic Advances in Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/20499361251403054","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/20499361251403054","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/20499361251403054","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:01:59Z","timestamp":1777593719000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/20499361251403054"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":17,"alternative-id":["10.1177\/20499361251403054"],"URL":"https:\/\/doi.org\/10.1177\/20499361251403054","relation":{},"ISSN":["2049-9361","2049-937X"],"issn-type":[{"value":"2049-9361","type":"print"},{"value":"2049-937X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12]]},"article-number":"20499361251403054"}}