{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T07:40:32Z","timestamp":1777880432273,"version":"3.51.4"},"reference-count":24,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["SAGE Open Medicine"],"published-print":{"date-parts":[[2014,1,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>The objective of this study was to evaluate the effectiveness of a nonsurgical treatment regimen in the long-term control of necrotic areas of the jaws and pain in such patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A total of 96 patients suffering from the disease were included in this study. All patients received nonsurgical treatment regimen for 10 days, and repeated every 3 months for 2 years. The size of the osteonecrotic lesions was measured and the pain level was self-assessed with a visual analog scale.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The patients showed a statistically significant (F = 16.1; p &lt; .01; r\n                      <jats:sup>2<\/jats:sup>\n                      = .95) gradual decrease in the size of exposed bone areas during the nonsurgical therapy (from 12.5 to 8.8 mm). Pain scores ranged from 0 to 3 score scale. Complete resolution of the disease was observed in some patients.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>This conservative nonsurgical treatment regimen seems to provide successful treatment in reduction of the sizes of exposed bone areas in the majority of patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/2050312114522995","type":"journal-article","created":{"date-parts":[[2014,2,18]],"date-time":"2014-02-18T22:24:48Z","timestamp":1392762288000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Efficacy of a nonsurgical treatment regimen in patients with bisphosphonate-related osteonecrosis of the jaws in Saudi Arabia"],"prefix":"10.1177","volume":"2","author":[{"given":"Mohammad M","family":"Alsehimy","sequence":"first","affiliation":[{"name":"Faculty of Dentistry, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2014,2,18]]},"reference":[{"key":"bibr1-2050312114522995","doi-asserted-by":"publisher","DOI":"10.5144\/0256-4947.2012.637"},{"key":"bibr2-2050312114522995","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-144-10-200605160-00009"},{"key":"bibr3-2050312114522995","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2007.01.008"},{"key":"bibr4-2050312114522995","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2006.11.003"},{"key":"bibr5-2050312114522995","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(06)70726-4"},{"key":"bibr6-2050312114522995","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2003.99.132"},{"key":"bibr7-2050312114522995","doi-asserted-by":"publisher","DOI":"10.1016\/S0278-2391(03)00328-8"},{"key":"bibr8-2050312114522995","doi-asserted-by":"publisher","DOI":"10.1016\/S0278-2391(03)00720-1"},{"key":"bibr9-2050312114522995","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2006.06.004"},{"key":"bibr10-2050312114522995","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2005.04.2465"},{"key":"bibr11-2050312114522995","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2006.08.004"},{"key":"bibr12-2050312114522995","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2005.07.010"},{"key":"bibr13-2050312114522995","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2007.08.025"},{"key":"bibr14-2050312114522995","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2007.08.003"},{"key":"bibr15-2050312114522995","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2011.07.004"},{"key":"bibr16-2050312114522995","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.0707onj"},{"key":"bibr17-2050312114522995","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctrv.2006.09.003"},{"key":"bibr18-2050312114522995","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2005.00842.x"},{"key":"bibr19-2050312114522995","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-0825.2007.01381.x"},{"key":"bibr20-2050312114522995","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2006.12.004"},{"key":"bibr21-2050312114522995","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2008.07504.x"},{"key":"bibr22-2050312114522995","first-page":"E318","volume":"13","author":"G\u00f3mez-Font R","year":"2008","journal-title":"Med Oral Patol Oral Cir Bucal"},{"key":"bibr23-2050312114522995","doi-asserted-by":"publisher","DOI":"10.1007\/s00428-007-0516-2"},{"key":"bibr24-2050312114522995","first-page":"88","volume":"15","author":"Hoshino H","year":"2005","journal-title":"Clin Calcium"}],"container-title":["SAGE Open Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2050312114522995","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2050312114522995","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2050312114522995","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:11:14Z","timestamp":1777594274000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2050312114522995"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1,1]]},"references-count":24,"alternative-id":["10.1177\/2050312114522995"],"URL":"https:\/\/doi.org\/10.1177\/2050312114522995","relation":{},"ISSN":["2050-3121","2050-3121"],"issn-type":[{"value":"2050-3121","type":"print"},{"value":"2050-3121","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,1,1]]},"article-number":"2050312114522995"}}