{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T07:43:02Z","timestamp":1777880582820,"version":"3.51.4"},"reference-count":19,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["SAGE Open Medicine"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>The aim of this study is to evaluate the efficacy and safety of non-invasive neurally adjusted ventilatory assist used after INtubation-SURfactant-Extubation in preterm infants with respiratory distress syndrome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We conducted a prospective observational study that included 15 inborn preterm infants at 28 (0\/7) to 33 (6\/7) weeks of gestation with respiratory distress syndrome in the period from April 2017 to October 2018. After INtubation-SURfactant-Extubation, infants underwent non-invasive neurally adjusted ventilatory assist. INtubation-SURfactant-Extubation failure was defined as follows: fraction of inspired oxygen requirement &gt;0.4, respiratory acidosis, and severe apnea within 5\u2009days after surfactant administration.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Two of the 15 (13.3%) infants showed INtubation-SURfactant-Extubation failure and required mechanical ventilation. No infants experienced any major complications such as pneumothorax, patent ductus arteriosus ligation, severe intraventricular hemorrhage, periventricular leukomalacia, retinopathy of prematurity, or death.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The rate of INtubation-SURfactant-Extubation failure when non-invasive neurally adjusted ventilatory assist was used after INtubation-SURfactant-Extubation for preterm infants with respiratory distress syndrome was 13.3%. Non-invasive neurally adjusted ventilatory assist can be safely performed without severe complications for preterm infants soon after birth.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/2050312119838417","type":"journal-article","created":{"date-parts":[[2019,3,15]],"date-time":"2019-03-15T08:34:41Z","timestamp":1552638881000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["The evaluation of the efficacy and safety of non-invasive neurally adjusted ventilatory assist in combination with INtubation-SURfactant-Extubation technique for infants at 28 to 33\u2009weeks of gestation with respiratory distress syndrome"],"prefix":"10.1177","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8384-7183","authenticated-orcid":false,"given":"Jun","family":"Miyahara","sequence":"first","affiliation":[{"name":"Department of Neonatology, Seirei Hamamatsu General Hospital, Hamamatsu, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Sugiura","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Seirei Hamamatsu General Hospital, Hamamatsu, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigeru","family":"Ohki","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Seirei Hamamatsu General Hospital, Hamamatsu, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,3,15]]},"reference":[{"key":"bibr1-2050312119838417","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199410203311603"},{"key":"bibr2-2050312119838417","doi-asserted-by":"publisher","DOI":"10.1542\/peds.103.2.e24"},{"key":"bibr3-2050312119838417","doi-asserted-by":"publisher","DOI":"10.1542\/peds.113.6.e560"},{"issue":"6","key":"bibr4-2050312119838417","first-page":"804","volume":"144","author":"Escobedo MB","year":"2004","journal-title":"J Pediatr"},{"key":"bibr5-2050312119838417","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jp.7211381"},{"key":"bibr6-2050312119838417","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jp.7211754"},{"key":"bibr7-2050312119838417","volume":"4","author":"Stevens TP","year":"2007","journal-title":"Cochrane Database Syst Rev"},{"key":"bibr8-2050312119838417","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2007-3501"},{"key":"bibr9-2050312119838417","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2015-3985"},{"key":"bibr10-2050312119838417","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2009.01348.x"},{"key":"bibr11-2050312119838417","doi-asserted-by":"publisher","DOI":"10.1038\/jp.2012.1"},{"key":"bibr12-2050312119838417","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.22883"},{"key":"bibr13-2050312119838417","first-page":"301818","volume":"2012","author":"Gizzi C","year":"2012","journal-title":"Crit Care Res Pract"},{"key":"bibr14-2050312119838417","doi-asserted-by":"publisher","DOI":"10.1203\/PDR.0b013e3181ff6770"},{"key":"bibr15-2050312119838417","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2014-308057"},{"key":"bibr16-2050312119838417","doi-asserted-by":"publisher","DOI":"10.1016\/j.siny.2016.01.006"},{"key":"bibr17-2050312119838417","doi-asserted-by":"publisher","DOI":"10.1038\/pr.2017.100"},{"key":"bibr18-2050312119838417","doi-asserted-by":"publisher","DOI":"10.1038\/s41372-018-0152-5"},{"key":"bibr19-2050312119838417","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.10708"}],"container-title":["SAGE Open Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2050312119838417","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2050312119838417","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2050312119838417","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:15:51Z","timestamp":1777594551000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2050312119838417"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1]]},"references-count":19,"alternative-id":["10.1177\/2050312119838417"],"URL":"https:\/\/doi.org\/10.1177\/2050312119838417","relation":{},"ISSN":["2050-3121","2050-3121"],"issn-type":[{"value":"2050-3121","type":"print"},{"value":"2050-3121","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,1]]},"article-number":"2050312119838417"}}