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Having been the most common non-ischemic cause of dilating cardiomyopathy in Latin America, it now spreads beyond the geographical boundaries of its vector via imported and autochthonous transmission. We review the evidence on surgery in Chagasic heart failure and offer a brief narrative on the main aspects of translational management. There is very limited literature on surgery for Chagasic heart failure, especially assist devices and transplantation. This may be attributed to the often unsurmountable economic burden of this single-system parasymphatholytic heart failure to young sufferers who commonly have very limited access to the aforementioned procedures. Chagasic heart failure offers a so far neglected translational model of parasymphatholytic non-ischemic cardiac failure.<\/jats:p>","DOI":"10.1177\/2050312119895927","type":"journal-article","created":{"date-parts":[[2019,12,18]],"date-time":"2019-12-18T07:01:22Z","timestamp":1576652482000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Translating Chagasic dilating cardiomyopathy to surgical therapies: An under published global challenge"],"prefix":"10.1177","volume":"7","author":[{"given":"Zoe C","family":"Groom","sequence":"first","affiliation":[{"name":"Costello Medical Consulting Limited, Cambridge, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vasileios","family":"Zochios","sequence":"additional","affiliation":[{"name":"Birmingham Acute Care Research Group, Institute of Inflammation and Ageing, Centre of Translational Inflammation Research, University of Birmingham, West 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