{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T18:24:16Z","timestamp":1787509456017,"version":"build-2736575974"},"reference-count":29,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Ministry of Science & Technology, Government of People\u2019s Republic of Bangladesh","award":["BS-20\/852"],"award-info":[{"award-number":["BS-20\/852"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["SAGE Open Medicine"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>The standard reference value of anti-streptolysin O (ASO) titre for diagnosing acute rheumatic fever (RF) in children is yet to be determined in Bangladesh. We aimed to measure the upper limit of the normal (ULN) of ASO titre among healthy children to determine the cut-off value for the diagnosis of RF in Bangladesh.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A total of 400 healthy children aged 5\u201315\u2009years with no history of fever, sore throat and impetigo during the last 8\u2009weeks of the study were enrolled. The respondents were randomly selected from an urban non-slum area, an urban slum area and a rural area of Bangladesh. ASO titre was measured using a turbidimetric immunoassay based on the principle of an agglutination reaction. The 80th percentile value was considered as the ULN of ASO titre.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Approximately 55% of the children were male. The mean (SD) age of children was 9.1 (2.7)\u2009years. The ULN of ASO titre for 5\u201315\u2009years aged children was 217.4\u2009IU\/mL.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Our reference value of ASO titre at the 80th percentile will be an essential guide for clinicians to diagnose acute RF.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/20503121221108558","type":"journal-article","created":{"date-parts":[[2022,6,28]],"date-time":"2022-06-28T05:25:47Z","timestamp":1656393947000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Study of streptococcal antibody (anti-streptolysin O) among healthy children in Bangladesh"],"prefix":"10.1177","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5402-3414","authenticated-orcid":false,"given":"Santosh Kumar","family":"Saha","sequence":"first","affiliation":[{"name":"National Institute of Cardiovascular Diseases and Hospital, Dhaka, Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamrun Nahar","family":"Choudhury","sequence":"additional","affiliation":[{"name":"National Center for Control of Rheumatic Fever and Heart Disease, Dhaka, Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salma","family":"Zareen","sequence":"additional","affiliation":[{"name":"National Center for Control of Rheumatic Fever and Heart Disease, Dhaka, Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabrina","family":"Mousum","sequence":"additional","affiliation":[{"name":"Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad Abdullah Al","family":"Mamun","sequence":"additional","affiliation":[{"name":"National Heart Foundation Hospital and Research Institute, Dhaka, Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M Atiqul","family":"Haque","sequence":"additional","affiliation":[{"name":"Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,6,28]]},"reference":[{"issue":"12","key":"bibr1-20503121221108558","first-page":"489","volume":"97","author":"Bavdekar SB","year":"1999","journal-title":"J Indian Med Assoc"},{"key":"bibr2-20503121221108558","doi-asserted-by":"publisher","DOI":"10.1001\/jama.268.15.2069"},{"key":"bibr3-20503121221108558","unstructured":"Johnson RD, Kaplan EL, Sramek J, et al. 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