{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T07:46:59Z","timestamp":1777880819142,"version":"3.51.4"},"reference-count":36,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["SAGE Open Medicine"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>To assess age at onset, delayed diagnosis and laterality of breast carcinoma among women at Debre Markos Comprehensive Specialized Hospital, North West Ethiopia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Hospital-based descriptive study was conducted on 120 breast carcinoma cases at pathology department of Debre Markos Comprehensive Specialized Hospital, from October 2019 to December 2021. The women aware of symptoms until first medical consultation time was asked. The height and weight of the women were measured using the height and weight scale. The attending physician examined both breasts and regional lymph nodes. Pathological features of breast carcinomas were recorded when biopsy results arrived at the pathology department. Data were entered in Epi data version 3.1. Then, it was exported to SPSS version 25.0 statistical software for analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Mean age of women was 39.9\u2009\u00b1\u200911.6\u2009years, and median age was 38\u2009years. Most women, 87 (72.5%) were aged less than 46\u2009years. One hundred three (85.8%) women had complained breast lump pain for greater than 3\u2009months before diagnosis. About 61 (50.8%) women had left breast carcinomas; 44 (36.7%) had right breast carcinomas and 15 (12.5%) had bilateral breast carcinomas. Of total, 53 (44.2%) cases were invasive ductal carcinomas; 41 (34.2%) had ductal carcinoma in situ; 14 (11.7%) were invasive lobular carcinomas; 8 (6.7%) were lobular carcinoma in situ and only 4 (3.3%) cases were mixed carcinomas.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>In this study, about two-third of the cases had early onset breast carcinoma. Most of the cases had delayed diagnosis of breast carcinoma. More than half of the cases had left breast carcinoma.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/20503121221114623","type":"journal-article","created":{"date-parts":[[2022,7,25]],"date-time":"2022-07-25T02:56:05Z","timestamp":1658717765000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Early onset, delayed diagnosis and laterality of breast carcinoma: Evidence from a tertiary care hospital"],"prefix":"10.1177","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9707-6439","authenticated-orcid":false,"given":"Bickes Wube","family":"Sume","sequence":"first","affiliation":[{"name":"Department of Biomedical Sciences, School of Medicine, Debre Markos University, Debre Markos, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5428-1624","authenticated-orcid":false,"given":"Wubshet","family":"Assefa","sequence":"additional","affiliation":[{"name":"Department of Pathology, School of Medicine, Debre Markos University, Debre Markos, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7612-4809","authenticated-orcid":false,"given":"Yoseph","family":"Merkeb Alamneh","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences, School of Medicine, Debre Markos University, Debre Markos, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,7,24]]},"reference":[{"key":"bibr1-20503121221114623","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamem.2006.05.015"},{"key":"bibr2-20503121221114623","first-page":"414","volume":"9","author":"Woldu M","year":"2017","journal-title":"J Cancer Sci Ther"},{"key":"bibr3-20503121221114623","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000003889"},{"key":"bibr4-20503121221114623","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2015.12783"},{"key":"bibr5-20503121221114623","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000017454"},{"key":"bibr6-20503121221114623","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2014-0493"},{"issue":"1","key":"bibr7-20503121221114623","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1756-0500-5-1","volume":"5","author":"Ermiah E","year":"2012","journal-title":"BMC Res Note"},{"key":"bibr8-20503121221114623","unstructured":"Federal Ministry of Health Ethiopia. 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