{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T06:33:40Z","timestamp":1778049220698,"version":"3.51.4"},"reference-count":23,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["SAGE Open Medicine"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>The study determined the rate of recent and past Toxoplasma gondii infections, associated factors, and awareness among expectant mothers assessing antenatal care in a tertiary hospital in Nigeria.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This prospective cohort study was conducted among pregnant women. A questionnaire was used to gather information on socio-demographics, infection risk factors, and awareness of the infection. Using an ELISA kit, the IgG and IgM antibodies against Toxoplasma gondii were assessed in blood samples from these women. For samples that tested positive for IgM, a real-time polymerase chain reaction was used to amplify the DNA. SPSS version 23 was used for data entry and analysis. The p-value\u2009&lt;\u20090.05 was adjudged to be significant.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>A total of 250 pregnant women participated in the study. The rate of recent infection (IgM antibody positivity) was 3.6% (9\/250), while past infection (IgG antibody positivity) was 68.4% (171\/250). Polymerase chain reaction confirmed 5\/9 recent infections as positive. Factors significantly associated with toxoplasmosis were gardening ( p\u2009=\u20090.037) and undercooked meat ( p\u2009=\u20090.023). Only 27 out of 250 pregnant women in this research had heard of toxoplasmosis, which translates to a low awareness rate of 10.8%.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>The recent infection among pregnant women in this study indicates the possibility of mother-to-child transmission with attendant sequelae. There was a significant association between past Toxoplasmosis gondii infections and stillbirth. Routine screening for toxoplasmosis should be incorporated into the antenatal program since none of the symptoms could significantly predict illness. In addition, regular antennal care instruction should cover toxoplasmosis education.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/20503121231202230","type":"journal-article","created":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T03:03:24Z","timestamp":1698635004000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Recent and past toxoplasmosis infections, associated factors, and awareness among pregnant women in Nigeria"],"prefix":"10.1177","volume":"11","author":[{"given":"Nnemelu Perpetua","family":"Onyinye","sequence":"first","affiliation":[{"name":"Department of Medical Microbiology and Parasitology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7779-4388","authenticated-orcid":false,"given":"Mbachu","family":"Ikechukwu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University, Nnewi Campus, Nnewi, Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ndukwe","family":"Chinedu","sequence":"additional","affiliation":[{"name":"Department of Anatomic Pathology and Forensic Medicine, Nnamdi Azikiwe University, Nnewi Campus, Nnewi, Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6510-4746","authenticated-orcid":false,"given":"Ogbuagu","family":"Chukwuanugo N","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology and Parasitology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Onyenyili Ikemefuna","family":"Nnamdi C","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology and Parasitology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akujobi Comfort","family":"Nne","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology and Parasitology, Nnamdi Azikiwe University, Nnewi Campus, Nnewi, Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,10,30]]},"reference":[{"key":"bibr1-20503121231202230","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)16412-X"},{"key":"bibr2-20503121231202230","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-019-3936-0"},{"key":"bibr3-20503121231202230","doi-asserted-by":"publisher","DOI":"10.2471\/BLT.12.111732"},{"key":"bibr4-20503121231202230","unstructured":"Mandell GL, Douglas RG, Bennett JE. 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