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Additionally, the frontal lobe is the largest brain lobe, making the localization of epileptic foci difficult, thereby preventing necessary surgery and improving seizure control. This review discusses the epidemiology and aetiology of drug-resistant frontal lobe epilepsy, demonstrating that cortical developmental manifestations constitute the most common aetiology of epileptic focus. Additionally, we reviewed the anatomy and symptoms of frontal lobe seizures. The review discusses advances in the neurophysiological study, including magnetoencephalography and neuroimaging modalities, such as quantitative PET scans and 7T MRI, for lesion detection and outcome improvement in frontal lobe epilepsy surgery. 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