{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T08:03:02Z","timestamp":1780128182029,"version":"3.54.0"},"reference-count":41,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Sage Open Medicine"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To systematically evaluate the impact of the COVID-19 pandemic, particularly lockdown (LD) periods, on the incidence, clinical presentations, surgical management, and outcomes of rhegmatogenous retinal detachment (RRD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A systematic literature search was conducted in PubMed, Embase, and Web of Science up to June 2025. Observational studies comparing RRD patients during COVID-19 LDs or pandemic periods with pre-pandemic controls were included. Outcomes assessed included RRD incidence, baseline clinical characteristics, intervals from symptom onset to first visit and surgery, surgical interventions, and anatomical and visual outcomes. Meta-analyses were performed for comparable outcomes using random- or fixed-effects models based on heterogeneity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Twenty-nine observational studies involving more than 116,000 eyes were included. COVID-19\u2013related restrictions were associated with a significant reduction in RRD surgical volume (rate ratio 0.71; 95% CI: 0.60\u20130.84), although marked regional heterogeneity was observed. Marked heterogeneity across studies appeared to be partly related to differences in LD severity, duration, and regional healthcare system burden. Patients presenting during LD periods were significantly less likely to have macula-on RRD (OR = 0.61; 95% CI: 0.46\u20130.83) and more likely to exhibit moderate-to-severe proliferative vitreoretinopathy (PVR) (OR = 2.58; 95% CI: 1.37\u20134.87) compared with pre-LD periods. Time from symptom onset to surgery increased during LD periods, while presentation-to-surgery intervals decreased. Surgical practice shifted toward greater use of pars plana vitrectomy (PPV), often combined with longer-acting gas tamponades or silicone oil. Despite increased disease severity, single-surgery retinal attachment rates and postoperative visual outcomes remained largely unchanged across periods.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The COVID-19 pandemic had substantial and region-specific effects on RRD management, influencing patient presentation patterns, disease severity, and surgical strategies. Nevertheless, adaptive healthcare responses helped preserve overall anatomical and visual outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/20503121261456478","type":"journal-article","created":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T09:59:46Z","timestamp":1779875986000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of COVID-19 pandemic on surgical volume, clinical presentations, and management of rhegmatogenous retinal detachment: A systematic review and meta-analysis"],"prefix":"10.1177","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0744-8337","authenticated-orcid":false,"given":"Hassan","family":"Asadigandomani","sequence":"first","affiliation":[{"name":"Farabi Eye Hospital"},{"name":"Tehran University of Medical Sciences"},{"name":"University of California San Francisco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Tahmasebi","sequence":"additional","affiliation":[{"name":"Tabriz University of Medical Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahan","family":"Jalilzadeh","sequence":"additional","affiliation":[{"name":"Tabriz University of Medical Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melika","family":"Arab Bafrani","sequence":"additional","affiliation":[{"name":"Farabi Eye Hospital"},{"name":"Tehran University of Medical Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatemeh","family":"Mahmoudi","sequence":"additional","affiliation":[{"name":"Farabi Eye Hospital"},{"name":"Tehran University of Medical Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimia","family":"Daneshvar","sequence":"additional","affiliation":[{"name":"Farabi Eye Hospital"},{"name":"Tehran University of Medical Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara Kamali","family":"Zonouzi","sequence":"additional","affiliation":[{"name":"Farabi Eye Hospital"},{"name":"Tehran University of Medical Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamid","family":"Riazi-Esfahani","sequence":"additional","affiliation":[{"name":"Farabi Eye Hospital"},{"name":"Tehran University of Medical Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elias","family":"Khalili Pour","sequence":"additional","affiliation":[{"name":"Farabi Eye Hospital"},{"name":"Tehran University of Medical Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,5,27]]},"reference":[{"key":"e_1_3_6_2_2","unstructured":"Organization WH. 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