{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T07:52:59Z","timestamp":1777881179472,"version":"3.51.4"},"reference-count":3,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Kanazawa Medical University Fund"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["SAGE Open Medical Case Reports"],"published-print":{"date-parts":[[2018,1,1]]},"abstract":"<jats:p>Optic nerve pilocytic astrocytoma is an uncommon but well-known entity; however, intraorbital ancient pilocytic astrocytoma of the optic nerve is extremely rarely reported. To our knowledge, this is the first detailed description regarding the intraorbital ancient pilocytic astrocytoma, reported in available English literature, to date. We presented an extremely unusual neurofibromatosis type 1 case of a 17-year-old male\u2019s sudden ocular pain secondary to intraorbital pilocytic astrocytoma of the optic nerve with markedly cystic degeneration, fluid production, and hemorrhage, due to ancient and possibly ruptured glioma. Future prospective studies are required to validate the significance of intraorbital ancient pilocytic astrocytoma arising from the optic nerve and the close correlation with ruptured cystic degeneration and ocular pain, after collecting and investigating a larger number of its cases examined.<\/jats:p>","DOI":"10.1177\/2050313x18761310","type":"journal-article","created":{"date-parts":[[2018,2,27]],"date-time":"2018-02-27T06:43:19Z","timestamp":1519713799000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Intraorbital ancient pilocytic astrocytoma of the optic nerve in neurofibromatosis type 1 patient presenting with sudden ocular pain"],"prefix":"10.1177","volume":"6","author":[{"given":"Haesu Lee","family":"Motoyama","sequence":"first","affiliation":[{"name":"Department of Pathology, Field of Oncology, Kagoshima University, Kagoshima, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2662-0024","authenticated-orcid":false,"given":"Sohsuke","family":"Yamada","sequence":"additional","affiliation":[{"name":"Department of Pathology, Field of Oncology, Kagoshima University, Kagoshima, Japan"},{"name":"Department of Pathology and Laboratory Medicine, Kanazawa Medical University, Ishikawa, Japan"},{"name":"Department of Pathology, Kanazawa Medical University Hospital, Ishikawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoko","family":"Nakada","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, Kanazawa Medical University, Ishikawa, Japan"},{"name":"Department of Pathology, Kanazawa Medical University Hospital, Ishikawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nozomu","family":"Kurose","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, Kanazawa Medical University, Ishikawa, Japan"},{"name":"Department of Pathology, Kanazawa Medical University Hospital, Ishikawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akihide","family":"Tanimoto","sequence":"additional","affiliation":[{"name":"Department of Pathology, Field of Oncology, Kagoshima University, Kagoshima, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2018,2,27]]},"reference":[{"key":"bibr1-2050313X18761310","doi-asserted-by":"crossref","first-page":"140","DOI":"10.55418\/1881041999","volume-title":"Tumors of the eye and ocular adnexa (atlas of tumor pathology)","author":"Font RL","year":"2006"},{"key":"bibr2-2050313X18761310","doi-asserted-by":"crossref","first-page":"89","DOI":"10.55418\/9781933477015","volume-title":"Tumors of the central nervous system (atlas of tumor pathology)","author":"Burger PC","year":"2007"},{"key":"bibr3-2050313X18761310","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1980.01020030501014"}],"container-title":["SAGE Open Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2050313X18761310","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2050313X18761310","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2050313X18761310","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:35:11Z","timestamp":1777595711000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2050313X18761310"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1,1]]},"references-count":3,"alternative-id":["10.1177\/2050313X18761310"],"URL":"https:\/\/doi.org\/10.1177\/2050313x18761310","relation":{},"ISSN":["2050-313X","2050-313X"],"issn-type":[{"value":"2050-313X","type":"print"},{"value":"2050-313X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,1,1]]},"article-number":"2050313X18761310"}}