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It manifests itself in painful blisters, erosions, and cracks and has a chronic course with frequent flares, significantly impacting patients\u2019 quality of life. Presently, there is no cure, but multiple treatment modalities are available. Most evidence supports treatment with topical steroids and antimicrobials. Treatment of recalcitrant disease has been shown to benefit from the addition of oral antibiotics, Naltrexone, systemic retinoids, botulinum toxin A injections, laser treatment, and surgical excision. We describe a case of refractory Hailey\u2013Hailey disease for which most of the abovementioned options failed, but which demonstrated significant improvement following a combination of oral acitretin and narrowband ultraviolet-B phototherapy. To achieve remission, the patient received 30 sessions three times per week with the increment of 20\u2009mJ\/cm<jats:sup>2<\/jats:sup> per session and oral acitretin 25\u2009mg PO daily. <\/jats:p>","DOI":"10.1177\/2050313x19845221","type":"journal-article","created":{"date-parts":[[2019,5,2]],"date-time":"2019-05-02T11:21:02Z","timestamp":1556796062000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":13,"title":["Treatment of Hailey\u2013Hailey disease with narrowband phototherapy and acitretin: A case report"],"prefix":"10.1177","volume":"7","author":[{"given":"Tatiana","family":"Lapa","sequence":"first","affiliation":[{"name":"Centre for Medical and Surgical Dermatology, Whitby, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maksym","family":"Breslavets","sequence":"additional","affiliation":[{"name":"Centre for Medical and Surgical Dermatology, Whitby, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,5,2]]},"reference":[{"key":"bibr1-2050313X19845221","first-page":"559","volume-title":"Andrews\u2019 diseases of the skin: clinical dermatology","author":"James WD","year":"2006","edition":"10"},{"key":"bibr2-2050313X19845221","doi-asserted-by":"publisher","DOI":"10.1038\/71701"},{"issue":"10","key":"bibr3-2050313X19845221","first-page":"1254","volume":"13","author":"Chiaravalloti AJ","year":"2014","journal-title":"J Drugs Dermatol"},{"key":"bibr4-2050313X19845221","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/9.7.1131"},{"key":"bibr5-2050313X19845221","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2008.381"},{"key":"bibr6-2050313X19845221","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.2003.12472.x"},{"key":"bibr7-2050313X19845221","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0781.2005.00173.x"},{"key":"bibr8-2050313X19845221","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-1390"},{"key":"bibr9-2050313X19845221","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2010.195"},{"key":"bibr10-2050313X19845221","doi-asserted-by":"publisher","DOI":"10.1007\/s00403-017-1751-2"},{"key":"bibr11-2050313X19845221","doi-asserted-by":"crossref","first-page":"589","DOI":"10.2340\/00015555-0529","volume":"88","author":"Ozdemir M","year":"2008","journal-title":"Clinical Report Acta Derm Venereol"},{"key":"bibr12-2050313X19845221","doi-asserted-by":"publisher","DOI":"10.1016\/j.mrgentox.2012.12.017"},{"key":"bibr13-2050313X19845221","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1989.tb01354.x"},{"key":"bibr14-2050313X19845221","doi-asserted-by":"publisher","DOI":"10.4081\/dr.2014.5604"},{"key":"bibr15-2050313X19845221","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.21784"},{"key":"bibr16-2050313X19845221","unstructured":"Wolverton SE. 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