{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T02:02:29Z","timestamp":1789524149113,"version":"build-2803163510"},"reference-count":6,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["SAGE Open Medical Case Reports"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:p> Bloom syndrome is a rare autosomal recessive disorder characterized by distinct physical features, such as short stature, genomic instability, and predisposition to numerous cancers. The BLM gene encodes for the RecQ helicase that plays an important role in genome editing, maintenance, and stability. Mutations in the BLM gene cause genomic instability that exposes the carriers to a variety of cancers, and in particular hematological and gastrointestinal cancers. Herein, we report the first case of pancreatic cancer in a 32-year-old patient with bloom syndrome. <\/jats:p>","DOI":"10.1177\/2050313x19855587","type":"journal-article","created":{"date-parts":[[2019,6,5]],"date-time":"2019-06-05T09:39:45Z","timestamp":1559727585000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Pancreatic cancer in bloom syndrome"],"prefix":"10.1177","volume":"7","author":[{"given":"Itai","family":"Tzfoni","sequence":"first","affiliation":[{"name":"Health Promotion Center and Integrated Cancer Prevention Center, Tel Aviv Sourasky Medical Center and Tel Aviv University, Tel Aviv, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Chayo","sequence":"additional","affiliation":[{"name":"Health Promotion Center and Integrated Cancer Prevention Center, Tel Aviv Sourasky Medical Center and Tel Aviv University, Tel Aviv, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meital","family":"Shaked","sequence":"additional","affiliation":[{"name":"Health Promotion Center and Integrated Cancer Prevention Center, Tel Aviv Sourasky Medical Center and Tel Aviv University, Tel Aviv, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1911-1969","authenticated-orcid":false,"given":"Ezra","family":"Bernstein","sequence":"additional","affiliation":[{"name":"Health Promotion Center and Integrated Cancer Prevention Center, Tel Aviv Sourasky Medical Center and Tel Aviv University, Tel Aviv, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roy","family":"Dekel","sequence":"additional","affiliation":[{"name":"Health Promotion Center and Integrated Cancer Prevention Center, Tel Aviv Sourasky Medical Center and Tel Aviv University, Tel Aviv, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3881-9228","authenticated-orcid":false,"given":"Nadir","family":"Arber","sequence":"additional","affiliation":[{"name":"Health Promotion Center and Integrated Cancer Prevention Center, Tel Aviv Sourasky Medical Center and Tel Aviv University, Tel Aviv, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiran","family":"Shapira","sequence":"additional","affiliation":[{"name":"Health Promotion Center and Integrated Cancer Prevention Center, Tel Aviv Sourasky Medical Center and Tel Aviv University, Tel Aviv, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2019,6,4]]},"reference":[{"issue":"6","key":"bibr1-2050313X19855587","first-page":"754","volume":"88","author":"Bloom D.","year":"1954","journal-title":"AMA Am J Dis Child"},{"key":"bibr2-2050313X19855587","doi-asserted-by":"publisher","DOI":"10.1101\/mcs.a002816"},{"key":"bibr3-2050313X19855587","doi-asserted-by":"publisher","DOI":"10.1159\/000375247"},{"key":"bibr4-2050313X19855587","doi-asserted-by":"publisher","DOI":"10.1089\/gte.1998.2.293"},{"key":"bibr5-2050313X19855587","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejim.2012.12.012"},{"key":"bibr6-2050313X19855587","doi-asserted-by":"publisher","DOI":"10.1159\/000452082"}],"container-title":["SAGE Open Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2050313X19855587","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2050313X19855587","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2050313X19855587","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T20:31:33Z","timestamp":1740861093000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2050313X19855587"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1]]},"references-count":6,"alternative-id":["10.1177\/2050313X19855587"],"URL":"https:\/\/doi.org\/10.1177\/2050313x19855587","relation":{},"ISSN":["2050-313X","2050-313X"],"issn-type":[{"value":"2050-313X","type":"print"},{"value":"2050-313X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,1]]},"article-number":"2050313X19855587"}}