{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T02:50:33Z","timestamp":1773283833157,"version":"3.50.1"},"reference-count":15,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["SAGE Open Medical Case Reports"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:sec><jats:title>Background:<\/jats:title><jats:p> Tuberculosis osteomyelitis is rarely seen in the diaphyseal bones. It may be confused with Brodie\u2019s abscess due to similar clinical, radiological and laboratory findings. Late diagnosis of the disease causes bone destruction. Tuberculosis osteomyelitis of the bone is a rare condition caused by the Mycobacterium tuberculosis. Its incidence has increased in Western countries in recent years due to HIV infection, increasing elderly population and emerging resistant strains. The slow progress of tuberculous osteomyelitis, due to lack of significant elevations in the laboratory values and changes in the radiographic appearance, often leads to confusion with the subtypes of subacute osteomyelitis, defined as Brodie\u2019s abscess. These two low-virulence clinical cases often lead to delays in diagnosis and progressive bone destruction. <\/jats:p><\/jats:sec><jats:sec><jats:title>Case presentation:<\/jats:title><jats:p> We report a 65-year-old male patient who presented to our clinic with pain, swelling and sensitivity in the left leg. Diagnosed with infection in the tibia, the patient had undergone antibiotherapy. However, the patient\u2019s symptoms were not resolved and we performed bone curettage and cementation. M. tuberculosis-specific DNA was detected by real-time polymerase chain reaction and the M. tuberculosis complex was produced from the perioperative samples. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p> In conclusion, histopathological examination and polymerase chain reaction are essential before surgery of subacute and chronic osteomyelitis with atypical clinical, laboratory and radiological findings for early diagnosis and accurate treatment. <\/jats:p><\/jats:sec>","DOI":"10.1177\/2050313x19869455","type":"journal-article","created":{"date-parts":[[2019,8,8]],"date-time":"2019-08-08T07:10:01Z","timestamp":1565248201000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Tuberculosis osteomyelitis of the tibia mimicking Brodie abscess: A case report and review of the literature"],"prefix":"10.1177","volume":"7","author":[{"given":"Abd\u00fclkadir","family":"Sari","sequence":"first","affiliation":[{"name":"Nam\u0131k Kemal University Faculty of Medicine Department of Orthopedics and Traumatology, Tekirdag, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6576-1802","authenticated-orcid":false,"given":"Ya\u015far Mahsut","family":"Din\u00e7el","sequence":"additional","affiliation":[{"name":"Nam\u0131k Kemal University Faculty of Medicine Department of Orthopedics and Traumatology, Tekirdag, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ibrahim Halil","family":"Erdogdu","sequence":"additional","affiliation":[{"name":"Adnan Menderes University Faculty of Medicine Department of Pathology, Aydin, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hakan Sezgin","family":"Say\u0131ner","sequence":"additional","affiliation":[{"name":"Adiyaman University School of Medicine Department of Department of Infectious Diseases Adiyaman, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ismail","family":"Agir","sequence":"additional","affiliation":[{"name":"Adiyaman University School of Medicine Department of Orthopedics and Traumatology, Adiyaman, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehmet \u00dcmit","family":"\u00c7etin","sequence":"additional","affiliation":[{"name":"Nam\u0131k Kemal University Faculty of Medicine Department of Orthopedics and Traumatology, Tekirdag, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,8,8]]},"reference":[{"key":"bibr1-2050313X19869455","doi-asserted-by":"publisher","DOI":"10.3944\/AOTT.2012.2698"},{"key":"bibr2-2050313X19869455","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.29309\/TPMJ\/2014.21.06.2729","volume":"21","author":"Khan GM","year":"2014","journal-title":"Professional Med J"},{"key":"bibr3-2050313X19869455","unstructured":"Global Tuberculosis Report, October 2017, https:\/\/www.who.int\/tb\/publications\/global_report\/gtbr2017_main_text.pdf"},{"issue":"6","key":"bibr4-2050313X19869455","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.29309\/TPMJ\/2014.21.06.2729","volume":"21","author":"Kaim Khan GM","year":"2014","journal-title":"Professional Med J"},{"issue":"4","key":"bibr5-2050313X19869455","first-page":"453","volume":"33","author":"Kao HK","year":"2010","journal-title":"Chang Gung Med J"},{"key":"bibr6-2050313X19869455","unstructured":"Khoshhal K, DeBerardino TM. 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