{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T13:41:03Z","timestamp":1753882863834,"version":"3.41.2"},"reference-count":8,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["SAGE Open Medical Case Reports"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:sec><jats:title>Introduction and objectives:<\/jats:title><jats:p> The main objective of this article is to present and discuss a case of localized ulcerative nodular amyloidosis with deep involvement clinically manifesting as ulcerative panniculitis and discuss its impact on the choice of treatment. <\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and results:<\/jats:title><jats:p> We present a 73-year-old woman with a history of painful ulcerated nodules on the inferior limbs. Microscopy confirmed amyloid deposits deep in the dermis and subcutaneous fat. No systemic involvement was found. Considering that skin-directed treatments often are not able to reach subcutaneous fat or were contraindicated because of the ulcers, she was successfully treated with cyclophosphamide and prednisone. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p> Localized ulcerative nodular amyloidosis with deep involvement is a rare clinical presentation that can present as ulcerative panniculitis. Such a clinical manifestation might be misleading. Systemic treatment might be necessary to control symptoms when conventional skin-directed therapies are contraindicated. <\/jats:p><\/jats:sec>","DOI":"10.1177\/2050313x19890755","type":"journal-article","created":{"date-parts":[[2019,11,29]],"date-time":"2019-11-29T13:57:25Z","timestamp":1575035845000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Localized ulcerative nodular amyloidosis presenting as ulcerative panniculitis, an unusual clinical manifestation: A case report"],"prefix":"10.1177","volume":"7","author":[{"given":"Carolina","family":"Fernandes","sequence":"first","affiliation":[{"name":"University of Sherbrooke, Sherbrooke, QC, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincent","family":"\u00c9thier","sequence":"additional","affiliation":[{"name":"University of Sherbrooke, Sherbrooke, QC, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sofia","family":"Marouan","sequence":"additional","affiliation":[{"name":"University of Sherbrooke, Sherbrooke, QC, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Myrna","family":"Chababi-Atallah","sequence":"additional","affiliation":[{"name":"University of Sherbrooke, Sherbrooke, QC, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Myl\u00e8ne","family":"Veilleux","sequence":"additional","affiliation":[{"name":"University of Sherbrooke, Sherbrooke, QC, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,11,29]]},"reference":[{"key":"bibr1-2050313X19890755","doi-asserted-by":"publisher","DOI":"10.1016\/j.ad.2011.05.017"},{"key":"bibr2-2050313X19890755","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000000861"},{"issue":"2","key":"bibr3-2050313X19890755","first-page":"87","volume":"84","author":"Schwendiman MN","year":"2009","journal-title":"Cutis"},{"key":"bibr4-2050313X19890755","doi-asserted-by":"publisher","DOI":"10.1016\/S0001-7310(05)73109-4"},{"key":"bibr5-2050313X19890755","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2008.04058.x"},{"key":"bibr6-2050313X19890755","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.139.9.1157"},{"key":"bibr7-2050313X19890755","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2001.04291.x"},{"issue":"2","key":"bibr8-2050313X19890755","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.annder.2015.10.596","volume":"143","author":"Gerard E","year":"2016","journal-title":"Ann Dermatol Venereol"}],"container-title":["SAGE Open Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2050313X19890755","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2050313X19890755","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2050313X19890755","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,28]],"date-time":"2025-02-28T20:05:54Z","timestamp":1740773154000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2050313X19890755"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1]]},"references-count":8,"alternative-id":["10.1177\/2050313X19890755"],"URL":"https:\/\/doi.org\/10.1177\/2050313x19890755","relation":{},"ISSN":["2050-313X","2050-313X"],"issn-type":[{"type":"print","value":"2050-313X"},{"type":"electronic","value":"2050-313X"}],"subject":[],"published":{"date-parts":[[2019,1]]},"article-number":"2050313X19890755"}}