{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T16:32:55Z","timestamp":1764174775037,"version":"3.41.2"},"reference-count":12,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["SAGE Open Medical Case Reports"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:p> Typhoid fever is endemic in developing countries like India. An increasing prevalence of resistance to cephalosporins and fluoroquinolones by Salmonella isolates is seen. We present an 8-month-old boy with invasive Salmonella typhi disease. Blood culture showed S. typhi sensitive to ampicillin\u2013sulbactam and cotrimoxazole but resistant to fluoroquinolones and third-generation cephalosporins. Cerebrospinal fluid examination revealed an aseptic meningitic picture. He was treated with intravenous meropenem and azithromycin following which his condition improved. This case highlights the need for improvement in environment sanitation and hygiene combined with early vaccination against typhoid fever and antimicrobial stewardship to help reduce the emerging resistance to cephalosporins and fluoroquinolones. <\/jats:p>","DOI":"10.1177\/2050313x20917835","type":"journal-article","created":{"date-parts":[[2020,4,27]],"date-time":"2020-04-27T17:57:24Z","timestamp":1588010244000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Cephalosporin-resistant typhoid"],"prefix":"10.1177","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5818-0791","authenticated-orcid":false,"given":"Noella Maria Delia","family":"Pereira","sequence":"first","affiliation":[{"name":"Department of Paediatrics, Bai Jerbai Wadia Hospital for Children, Mumbai, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ira","family":"Shah","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Bai Jerbai Wadia Hospital for Children, Mumbai, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,4,27]]},"reference":[{"key":"bibr1-2050313X20917835","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dki116"},{"key":"bibr2-2050313X20917835","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkt469"},{"key":"bibr3-2050313X20917835","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijmm.2016.11.006"},{"key":"bibr4-2050313X20917835","unstructured":"World Health Organization (WHO). Guidelines for the management of typhoid fever. Geneva: WHO, 2011, http:\/\/apps.who.int\/medicinedocs\/documents\/s20994en\/s20994en.pdf (accessed 1 February 2020)."},{"key":"bibr5-2050313X20917835","doi-asserted-by":"publisher","DOI":"10.1007\/s10156-006-0472-9"},{"key":"bibr6-2050313X20917835","first-page":"1491","volume-title":"Feigin and Cherry\u2019s: Textbook of pediatric infectious diseases","author":"Ochoa T","year":"2014","edition":"7"},{"issue":"6","key":"bibr7-2050313X20917835","first-page":"805","volume":"30","author":"Garg RA","year":"1993","journal-title":"Indian Pediatr"},{"key":"bibr8-2050313X20917835","doi-asserted-by":"publisher","DOI":"10.3855\/jidc.3030"},{"key":"bibr9-2050313X20917835","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0132065"},{"key":"bibr10-2050313X20917835","doi-asserted-by":"publisher","DOI":"10.1177\/0009922819881203"},{"issue":"5","key":"bibr11-2050313X20917835","first-page":"e4664","volume":"11","author":"Bhatti JM","year":"2019","journal-title":"Cureus"},{"key":"bibr12-2050313X20917835","doi-asserted-by":"publisher","DOI":"10.1088\/1755-1315\/125\/1\/012091"}],"container-title":["SAGE Open Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2050313X20917835","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2050313X20917835","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2050313X20917835","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,2]],"date-time":"2025-03-02T19:55:03Z","timestamp":1740945303000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2050313X20917835"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1]]},"references-count":12,"alternative-id":["10.1177\/2050313X20917835"],"URL":"https:\/\/doi.org\/10.1177\/2050313x20917835","relation":{},"ISSN":["2050-313X","2050-313X"],"issn-type":[{"type":"print","value":"2050-313X"},{"type":"electronic","value":"2050-313X"}],"subject":[],"published":{"date-parts":[[2020,1]]},"article-number":"2050313X20917835"}}