{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T14:25:51Z","timestamp":1761920751307,"version":"3.41.2"},"reference-count":12,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["SAGE Open Medical Case Reports"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:p> Appearance of endometrial carcinoma in pericardial effusion is extremely rare. Its major etiological factors include lung cancer, breast cancer, lymphoma, and leukemia. We herein report a case of a large malignant pericardial effusion 7\u2009years after surgery for endometrial carcinoma. A 66-year-old woman who underwent modified radical hysterectomy, bilateral salpingo-oophorectomy, and lymph node dissection for endometrial carcinoma 7\u2009years ago and who had self-interrupted subsequent chemotherapy was presented with vertigo and vomiting. Chest computed tomography revealed pericardial effusion. Cytological examination diagnosed it as adenocarcinoma with psammoma bodies and mitoses. Immunohistochemistry analysis revealed that adenocarcinoma cells were positive for p53, p16, and insulin-like growth factor II mRNA-binding protein-3, but negative for estrogen receptor. Adenocarcinoma cells in pericardial effusion were morphologically and immunohistochemically similar to the serous carcinoma component of the surgical specimen. The appearance of psammoma bodies in cytological examination triggered the diagnosis. <\/jats:p>","DOI":"10.1177\/2050313x20930919","type":"journal-article","created":{"date-parts":[[2020,6,11]],"date-time":"2020-06-11T04:59:22Z","timestamp":1591851562000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Case report of large malignant pericardial effusion in a post-surgical setting of endometrial mixed carcinoma: A description of unique cytological, histological, and immunohistochemical findings"],"prefix":"10.1177","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0636-9058","authenticated-orcid":false,"given":"Seiya","family":"Mizuguchi","sequence":"first","affiliation":[{"name":"Department of Pathology, Kanazawa Medical University Hospital, Ishikawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1863-5368","authenticated-orcid":false,"given":"Akihiro","family":"Shioya","sequence":"additional","affiliation":[{"name":"Department of Pathology, Kanazawa Medical University Hospital, Ishikawa, Japan"},{"name":"Departments of Pathology and Laboratory Medicine, Kanazawa Medical University, Ishikawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshiyuki","family":"Sasagawa","sequence":"additional","affiliation":[{"name":"Department of Reproductive and Perinatal Medicine, Kanazawa Medical University, Ishikawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sumire","family":"Yamada","sequence":"additional","affiliation":[{"name":"Department of Reproductive and Perinatal Medicine, Kanazawa Medical University, Ishikawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2742-5693","authenticated-orcid":false,"given":"Kenichi","family":"Mizutani","sequence":"additional","affiliation":[{"name":"Department of Pathology, Kanazawa Medical University Hospital, Ishikawa, Japan"},{"name":"Departments of Pathology and Laboratory Medicine, Kanazawa Medical University, Ishikawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3626-4633","authenticated-orcid":false,"given":"Nozomu","family":"Kurose","sequence":"additional","affiliation":[{"name":"Department of Pathology, Kanazawa Medical University Hospital, Ishikawa, Japan"},{"name":"Departments of Pathology and Laboratory Medicine, Kanazawa Medical University, Ishikawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2662-0024","authenticated-orcid":false,"given":"Sohsuke","family":"Yamada","sequence":"additional","affiliation":[{"name":"Department of Pathology, Kanazawa Medical University Hospital, Ishikawa, Japan"},{"name":"Departments of Pathology and Laboratory Medicine, Kanazawa Medical University, Ishikawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,6,10]]},"reference":[{"key":"bibr1-2050313X20930919","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmcr.2019.01.011"},{"key":"bibr2-2050313X20930919","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000017584"},{"key":"bibr3-2050313X20930919","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-6196(11)65028-3"},{"key":"bibr4-2050313X20930919","doi-asserted-by":"publisher","DOI":"10.1016\/0090-8258(88)90218-1"},{"key":"bibr5-2050313X20930919","doi-asserted-by":"publisher","DOI":"10.1006\/gyno.2001.6351"},{"key":"bibr6-2050313X20930919","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejim.2004.02.005"},{"key":"bibr7-2050313X20930919","doi-asserted-by":"publisher","DOI":"10.1006\/gyno.2001.6340"},{"key":"bibr8-2050313X20930919","doi-asserted-by":"publisher","DOI":"10.1006\/gyno.1995.1078"},{"key":"bibr9-2050313X20930919","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-008-0701-9"},{"key":"bibr10-2050313X20930919","unstructured":"Kurman RJ, Carcangiu ML, Herrington CS, et al. WHO classification of tumours of female reproductive organs. 4th ed. 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