{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T13:41:06Z","timestamp":1753882866555,"version":"3.41.2"},"reference-count":76,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["SAGE Open Medical Case Reports"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:p> This case report illustrates the treatment outcomes of a collegiate athlete presenting with an 18-month history of post-concussion syndrome who received a series of mixed manual therapies in isolation of other therapy. Persistent symptoms were self-reported as debilitating, contributing to self-removal from participation in school, work, and leisure activities. Patient and parent interviews captured the history of multiple concussions and other sports-related injuries. Neurological screening and activities of daily living were baseline measured. Post-Concussion Symptom Checklist and Headache Impact Test-6\u2122 were utilized to track symptom severity. Treatments applied included craniosacral therapy, manual lymphatic drainage, and glymphatic techniques. Eleven treatment sessions were administered over 3 months. Results indicated restoration of oxygen saturation, normalized pupil reactivity, and satisfactory sleep. Post-concussion syndrome symptom severity was reduced by 87% as reflected by accumulative Post-Concussion Symptom Checklist scores. Relief from chronic headaches was achieved, reflected by Headache Impact Test-6 scores. Restoration of mood and quality of life were reported. A 6-month follow-up revealed symptoms remained abated with full re-engagement of daily activities. The author hypothesized that post-concussion syndrome symptoms were related to compression of craniosacral system structures and lymphatic fluid stagnation that contributed to head pressure pain, severe sleep deprivation, and multiple neurological and psychological symptoms. Positive outcomes over a relatively short period of time without adverse effects suggest these therapies may offer viable options for the treatment of post-concussion syndrome. <\/jats:p>","DOI":"10.1177\/2050313x20952224","type":"journal-article","created":{"date-parts":[[2021,1,21]],"date-time":"2021-01-21T08:02:27Z","timestamp":1611216147000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Case report: Manual therapies promote resolution of persistent post-concussion symptoms in a 24-year-old athlete"],"prefix":"10.1177","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2018-8365","authenticated-orcid":false,"given":"Susan Vaughan","family":"Kratz","sequence":"first","affiliation":[{"name":"Registered Occupational Therapist, CranioSacral Therapy\u2014Diplomat, Special Therapies, Inc., Waukesha, WI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,1,21]]},"reference":[{"key":"bibr1-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports-2018-100338"},{"key":"bibr2-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2017.00513"},{"key":"bibr3-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1016\/j.nec.2016.05.005"},{"key":"bibr4-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1201\/9781315119328"},{"key":"bibr5-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports-2017-097699"},{"key":"bibr6-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports-2015-095564"},{"key":"bibr7-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1249\/JSR.0000000000000573"},{"issue":"2","key":"bibr8-2050313X20952224","first-page":"286","volume":"12","author":"Lundblad M.","year":"2017","journal-title":"Int J Sports Phys Ther"},{"key":"bibr9-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1017\/S1355617712000872"},{"key":"bibr10-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1186\/2045-8118-11-10"},{"key":"bibr11-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1016\/j.tins.2003.08.008"},{"key":"bibr12-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.2176\/nmc.ra.2016-0020"},{"key":"bibr13-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1172\/JCI67677"},{"key":"bibr14-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-pathol-051217-111018"},{"key":"bibr15-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1007\/s11064-015-1581-6"},{"volume-title":"Brain stars: glia illuminating craniosacral therapy","year":"2015","author":"Wanveer T.","key":"bibr16-2050313X20952224"},{"key":"bibr17-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1172\/JCI90603"},{"key":"bibr18-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3003748"},{"key":"bibr19-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1186\/1479-5876-11-107"},{"key":"bibr20-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-018-1812-4"},{"key":"bibr21-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1038\/nature14432"},{"key":"bibr22-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1097\/01.NT.0000469526.77988.9e"},{"key":"bibr23-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-25666-4"},{"key":"bibr24-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20142290"},{"key":"bibr25-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2013.06.022"},{"key":"bibr26-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3742-14.2015"},{"key":"bibr27-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1089\/neu.2012.2650"},{"key":"bibr28-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2018.09.022"},{"key":"bibr29-2050313X20952224","first-page":"199","volume-title":"A touch better: two therapists\u2019 journey and the lessons they learned from Dr. John E. Upledger about craniosacral therapy","author":"Breman GM","year":"2019"},{"key":"bibr30-2050313X20952224","unstructured":"Upledger JE, Vredevoogd JD. Craniosacral therapy. Seattle, WA: Eastland Press, 1983, pp. 77\u201387."},{"key":"bibr31-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1089\/neu.2015.3937"},{"issue":"3","key":"bibr32-2050313X20952224","first-page":"54","volume":"15","author":"Whedon JM","year":"2009","journal-title":"Altern Ther Health Med"},{"key":"bibr33-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1023\/A:1011071115227"},{"key":"bibr34-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.7556\/jaoa.1995.95.3.182"},{"key":"bibr35-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1516539"},{"key":"bibr36-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.3109\/02688697.2016.1173191"},{"key":"bibr37-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00695.2001"},{"volume-title":"Complementary therapies in rehabilitation: evidence for efficacy in therapy, prevention, and wellness","year":"2009","author":"Davis CM","key":"bibr38-2050313X20952224"},{"volume-title":"Cranial manipulation: theory and practice: osseous and soft tissue approaches","year":"2005","author":"Chaitow L.","key":"bibr39-2050313X20952224"},{"key":"bibr40-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1080\/08869634.2002.11746188"},{"key":"bibr41-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1177\/028418519303400403"},{"key":"bibr42-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.2519\/jospt.2006.36.11.845"},{"key":"bibr43-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1080\/08869634.1992.11677885"},{"issue":"10","key":"bibr44-2050313X20952224","first-page":"457","volume":"105","author":"Chikly BJ.","year":"2005","journal-title":"J Am Osteopath Assoc"},{"volume-title":"Silent waves: theory and practice of lymph drainage therapy: an osteopathic lymphatic technique","year":"2004","author":"Chikly B","key":"bibr45-2050313X20952224"},{"key":"bibr46-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2011.02.018"},{"key":"bibr47-2050313X20952224","first-page":"901","volume":"143","author":"Cris\u00f3stomo RS","year":"2017","journal-title":"Clin Phys Therapy"},{"key":"bibr48-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1123\/jsr.2014-0222"},{"key":"bibr49-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1179\/jmt.2009.17.3.80E"},{"issue":"2","key":"bibr50-2050313X20952224","first-page":"36","volume":"17","author":"Trettin H.","year":"1993","journal-title":"Z Lymphol"},{"key":"bibr51-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-7166.2012.01174.x"},{"key":"bibr52-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctim.2012.07.009"},{"key":"bibr53-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctim.2014.09.007"},{"key":"bibr54-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1089\/acu.2017.1222"},{"key":"bibr55-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbmt.2015.03.006"},{"key":"bibr56-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.31636\/pmjua.t1.21299"},{"key":"bibr57-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.7556\/jaoa.2016.036"},{"key":"bibr58-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1089\/acm.2013.0283"},{"key":"bibr59-2050313X20952224","unstructured":"Rice LL. Upledger institute case study CranioSacral therapy \u2014traumatic brain injuries, 2017, https:\/\/www.iahe.com\/docs\/articles\/craniosacral-therapy\u2014\u2013traumatic-brain-injuries\u2013tbi-pdf"},{"key":"bibr60-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports-2016-097470"},{"key":"bibr61-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.7556\/jaoa.2017.011"},{"key":"bibr62-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.15406\/mojypt.2017.02.00031"},{"issue":"1","key":"bibr63-2050313X20952224","first-page":"5","volume":"1","author":"Kratz SV.","year":"2016","journal-title":"J Pain"},{"issue":"3","key":"bibr64-2050313X20952224","first-page":"341","volume":"6","author":"Fac\u00f3 SG","year":"2016","journal-title":"Revista Pesquisa Em Fisioterapia"},{"issue":"1","key":"bibr65-2050313X20952224","first-page":"35","volume":"3","author":"Eugene AR","year":"2015","journal-title":"Medtube Sci"},{"key":"bibr66-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2017.08.016"},{"key":"bibr67-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1126\/science.1241224"},{"key":"bibr68-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.4085\/1062-6050-47.2.221"},{"key":"bibr69-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1093\/arclin\/acp025"},{"key":"bibr70-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1207\/s15324826an1303_4"},{"key":"bibr71-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1136\/bjsm.2009.058339"},{"key":"bibr72-2050313X20952224","unstructured":"Post-Concussion Symptom Checklist, 2017, https:\/\/www.education.ne.gov\/wp-content\/uploads\/2017\/07\/Post-Concussion_Symptom_Checklist.pdf"},{"key":"bibr73-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1023\/A:1026119331193"},{"key":"bibr74-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1177\/0333102410379890"},{"key":"bibr75-2050313X20952224","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2005.05130.x"},{"issue":"9","key":"bibr76-2050313X20952224","first-page":"928","volume":"70","author":"Frymann VM.","year":"1971","journal-title":"J Am Osteopath Assoc"}],"container-title":["SAGE Open Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2050313X20952224","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2050313X20952224","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2050313X20952224","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,2]],"date-time":"2025-03-02T10:46:44Z","timestamp":1740912404000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2050313X20952224"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":76,"alternative-id":["10.1177\/2050313X20952224"],"URL":"https:\/\/doi.org\/10.1177\/2050313x20952224","relation":{},"ISSN":["2050-313X","2050-313X"],"issn-type":[{"type":"print","value":"2050-313X"},{"type":"electronic","value":"2050-313X"}],"subject":[],"published":{"date-parts":[[2021,1]]},"article-number":"2050313X20952224"}}