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Herein, we present the case of a 68-year-old female with ulcerative colitis who underwent a subtotal colectomy with an end-ileostomy and presented post-operatively with large, multifocal pyoderma gangrenosum at two abdominal sites. She was managed with intralesional triamcinolone injections and high-dose systemic steroids and was transitioned to IV infliximab. Our case report illustrates the role of infliximab in the treatment of complicated multifocal pyoderma gangrenosum and contemplates the impact of systemic infliximab exposure. <\/jats:p>","DOI":"10.1177\/2050313x20964113","type":"journal-article","created":{"date-parts":[[2020,10,23]],"date-time":"2020-10-23T11:54:42Z","timestamp":1603454082000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Infliximab treatment for large, multifocal, abdominal pyoderma gangrenosum associated with ulcerative colitis: A case report"],"prefix":"10.1177","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8163-2266","authenticated-orcid":false,"given":"Maria","family":"Mikail","sequence":"first","affiliation":[{"name":"Schulich School of Medicine & Dentistry, Health Sciences Addition, Western University, London, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6568-1714","authenticated-orcid":false,"given":"Aze","family":"Wilson","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Gastroenterology, Western University, London, ON, Canada"},{"name":"Department of Medicine, Division of Clinical Pharmacology, Western University, London, ON, Canada"},{"name":"Department of Physiology & Pharmacology, Western University, London, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,10,23]]},"reference":[{"key":"bibr1-2050313X20964113","doi-asserted-by":"crossref","unstructured":"Schadt C. 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