{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T14:42:55Z","timestamp":1791297775006,"version":"4.1.0"},"reference-count":30,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["SAGE Open Medical Case Reports"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:p> \u03b2-mannosidosis is a rare autosomal recessive lysosomal storage disease of glycoprotein catabolism caused by a deficiency of \u03b2-mannosidase. Clinical presentation includes intellectual deficits, hearing loss, and recurrent respiratory infections. This report describes the dental treatment and follow-up dental care of a child with \u03b2-mannosidosis. The patient presented to the dental clinic at the age of 6\u2009years with a localized swelling of his lower posterior teeth. Sickle cell disease and physical and mental developmental delays were noted. Clinical examination revealed a flattened nasal bridge, large head, short neck, open bite, gingival overgrowth, macroglossia, enlarged pulp chambers, and poor oral hygiene. Surgical treatment under general anesthesia included extractions, pulp therapy, and restorations. Four years later, the child returned with generalized gingival inflammation and new carious lesions. Periodontal and restorative treatment was provided, and a preventive dental regimen was established. Mannosidosis cases require complex dental procedures, consultations, and prompt follow-up. <\/jats:p>","DOI":"10.1177\/2050313x211065796","type":"journal-article","created":{"date-parts":[[2021,12,15]],"date-time":"2021-12-15T10:10:06Z","timestamp":1639563006000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Oral manifestation and dental treatment of pediatric patient with beta-mannosidosis: A case report"],"prefix":"10.1177","volume":"9","author":[{"given":"Mohammad A","family":"Alshoraim","sequence":"first","affiliation":[{"name":"Department of Pediatric Dentistry, East Jeddah General Hospital, Jeddah, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0214-5479","authenticated-orcid":false,"given":"Dania E","family":"Al Agili","sequence":"additional","affiliation":[{"name":"Department of Dental Public Health, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,12,15]]},"reference":[{"key":"bibr1-2050313X211065796","doi-asserted-by":"publisher","DOI":"10.1007\/s004399900075"},{"key":"bibr2-2050313X211065796","doi-asserted-by":"publisher","DOI":"10.1007\/s10545-010-9093-7"},{"key":"bibr3-2050313X211065796","doi-asserted-by":"publisher","DOI":"10.5144\/0256-4947.2004.393"},{"key":"bibr4-2050313X211065796","doi-asserted-by":"publisher","DOI":"10.1007\/BF01804251"},{"issue":"3","key":"bibr5-2050313X211065796","volume":"5","author":"Blomqvist M","year":"2019","journal-title":"Mole Case Stud"},{"key":"bibr6-2050313X211065796","doi-asserted-by":"publisher","DOI":"10.21037\/atm.2018.11.39"},{"key":"bibr7-2050313X211065796","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2008.09.007"},{"key":"bibr8-2050313X211065796","doi-asserted-by":"publisher","DOI":"10.1007\/BF01800211"},{"key":"bibr9-2050313X211065796","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2007.01.037"},{"key":"bibr10-2050313X211065796","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1992.tb03408.x"},{"key":"bibr11-2050313X211065796","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2004.tb00630.x"},{"key":"bibr12-2050313X211065796","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2003.05365.x"},{"key":"bibr13-2050313X211065796","doi-asserted-by":"publisher","DOI":"10.1007\/8904_2013_227"},{"key":"bibr14-2050313X211065796","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410350119"},{"key":"bibr15-2050313X211065796","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymgme.2006.07.001"},{"key":"bibr16-2050313X211065796","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph14030281"},{"key":"bibr17-2050313X211065796","doi-asserted-by":"publisher","DOI":"10.1007\/s10545-013-9645-8"},{"key":"bibr18-2050313X211065796","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2011.07.013"},{"key":"bibr19-2050313X211065796","doi-asserted-by":"publisher","DOI":"10.1002\/9781118852446"},{"key":"bibr20-2050313X211065796","unstructured":"National Center for Health Statistics, Centers for Disease Control and Prevention. 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