{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T13:40:29Z","timestamp":1753882829388,"version":"3.41.2"},"reference-count":18,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["SAGE Open Medical Case Reports"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:p> Coronavirus disease-19 (COVID-19) was first identified in Wuhan, China, and spread gradually throughout the world. There are multiple reports of prolonged viral shedding in people infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); however, such findings have not been documented in Bangladesh. Herein, we present a case of metabolic syndrome that remained positive for SARS-CoV-2 RNA over a prolonged period. On clinical and laboratory examination, the patient was diagnosed with obesity, raised blood pressure, dyslipidemia, and uncontrolled glycemia. However, upon taking appropriate measures and controlling the plasma sugar level, he tested negative for SARS-CoV-2 RNA on the 72nd day since illness onset. We observed that COVID-19 patients with several comorbidities, such as metabolic syndrome, may shed the virus over a prolonged period. Therefore, strict public health measures and isolation rules should be followed by a high-risk population. <\/jats:p>","DOI":"10.1177\/2050313x21989492","type":"journal-article","created":{"date-parts":[[2021,1,23]],"date-time":"2021-01-23T09:23:09Z","timestamp":1611393789000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Persistence of SARS-CoV-2 RNA in a male with metabolic syndrome for 72 days: A case report"],"prefix":"10.1177","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8164-5905","authenticated-orcid":false,"given":"SM Rashed Ul","family":"Islam","sequence":"first","affiliation":[{"name":"Department of Virology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tahmina","family":"Akther","sequence":"additional","affiliation":[{"name":"Department of Virology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sharmin","family":"Sultana","sequence":"additional","affiliation":[{"name":"Department of Virology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saif Ullah","family":"Munshi","sequence":"additional","affiliation":[{"name":"Department of Virology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,1,23]]},"reference":[{"key":"bibr1-2050313X21989492","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2001017"},{"key":"bibr2-2050313X21989492","unstructured":"Directorate General of Health Services. Coronavirus COVID-19 dashboard, http:\/\/103.247.238.92\/webportal\/pages\/covid19.php (2020, accessed 13 September 2020)."},{"key":"bibr3-2050313X21989492","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30154-9"},{"key":"bibr4-2050313X21989492","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2020.05.045"},{"key":"bibr5-2050313X21989492","doi-asserted-by":"publisher","DOI":"10.1177\/1074248416686187"},{"key":"bibr6-2050313X21989492","unstructured":"Directorate General of Health Services Ministry of Health Family Welfare. National Guidelines on clinical management of coronavirus disease 2019 (COVID-19), Version 7.0, p. 39, https:\/\/www.dghs.gov.bd\/images\/docs\/Guideline\/COVID_Guideline_v7.pdf (2020, accessed 30 June 2020)."},{"issue":"2","key":"bibr7-2050313X21989492","first-page":"318","volume":"81","author":"Liu WD","year":"2020","journal-title":"J Infect"},{"key":"bibr8-2050313X21989492","doi-asserted-by":"publisher","DOI":"10.1016\/j.transci.2020.102871"},{"key":"bibr9-2050313X21989492","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2020.03.039"},{"key":"bibr10-2050313X21989492","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMp2025631"},{"key":"bibr11-2050313X21989492","unstructured":"CDC. Coronavirus Disease 2019 (COVID-19). Centers for Disease Control and Prevention, https:\/\/www.cdc.gov\/coronavirus\/2019-ncov\/hcp\/duration-isolation.html?CDC_AA_refVal=https%3A%2F%2Fwww.cdc.gov%2Fcoronavirus%2F2019-ncov%2Fcommunity%2Fstrategy-discontinue-isolation.html (2020, accessed 10 November 2020)."},{"key":"bibr12-2050313X21989492","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2020.06.015"},{"key":"bibr13-2050313X21989492","doi-asserted-by":"publisher","DOI":"10.1016\/j.metabol.2020.154244"},{"key":"bibr14-2050313X21989492","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2020.03.044"},{"key":"bibr15-2050313X21989492","doi-asserted-by":"publisher","DOI":"10.1016\/j.dsx.2020.04.049"},{"key":"bibr16-2050313X21989492","doi-asserted-by":"publisher","DOI":"10.1016\/j.isci.2020.101425"},{"key":"bibr17-2050313X21989492","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2020.04.021"},{"key":"bibr18-2050313X21989492","unstructured":"US National Library of Medicine ClinicalTrials.gov. A comparative study on ivermectin and hydroxychloroquine on the COVID19 patients in Bangladesh, https:\/\/clinicaltrials.gov\/ct2\/show\/NCT04434144 (accessed 2 September 2020)."}],"container-title":["SAGE Open Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2050313X21989492","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2050313X21989492","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2050313X21989492","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,3]],"date-time":"2025-03-03T16:35:23Z","timestamp":1741019723000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2050313X21989492"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":18,"alternative-id":["10.1177\/2050313X21989492"],"URL":"https:\/\/doi.org\/10.1177\/2050313x21989492","relation":{},"ISSN":["2050-313X","2050-313X"],"issn-type":[{"type":"print","value":"2050-313X"},{"type":"electronic","value":"2050-313X"}],"subject":[],"published":{"date-parts":[[2021,1]]},"article-number":"2050313X21989492"}}