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After an appendectomy, the abdominal pain did not resolve. He later developed orthopnea, bilateral lower limb pitting edema, and bilateral fine basal crepitations. This pointed to MIS-C. We should be mindful of multisystem inflammatory syndrome in children in children with a recent history of COVID-19. <\/jats:p>","DOI":"10.1177\/2050313x221082903","type":"journal-article","created":{"date-parts":[[2022,3,5]],"date-time":"2022-03-05T10:14:15Z","timestamp":1646475255000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["The rising appendicitis mimicker: A case report of Multisystem Inflammatory Syndrome in Children presenting with acute abdomen"],"prefix":"10.1177","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9283-2001","authenticated-orcid":false,"given":"Esraa O","family":"Salaheldin","sequence":"first","affiliation":[{"name":"El-Demerdash Hospital, Ain Shams University, Cairo, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1003-7785","authenticated-orcid":false,"given":"Reham A","family":"Lasheen","sequence":"additional","affiliation":[{"name":"El-Demerdash Hospital, Ain Shams University, Cairo, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8658-0648","authenticated-orcid":false,"given":"Abdelrahman","family":"ElTohamy","sequence":"additional","affiliation":[{"name":"El-Demerdash Hospital, Ain Shams University, Cairo, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,3,5]]},"reference":[{"key":"bibr1-2050313X221082903","unstructured":"Centers for Disease Control and Prevention. Multisystem Inflammatory Syndrome in Children (MIS-C) associated with Coronavirus Disease 2019 (COVID-19), https:\/\/emergency.cdc.gov\/han\/2020\/han00432.asp (2020, accessed 30 June 2021)."},{"key":"bibr2-2050313X221082903","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)31094-1"},{"key":"bibr3-2050313X221082903","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2021756"},{"key":"bibr4-2050313X221082903","doi-asserted-by":"publisher","DOI":"10.1038\/s41390-021-01545-z"},{"key":"bibr5-2050313X221082903","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2020201473"},{"key":"bibr6-2050313X221082903","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2010.08122.x"},{"key":"bibr7-2050313X221082903","unstructured":"Otto M, Nagalli S. Mesenteric adenitis. In: StatPearls. 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