{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T13:40:24Z","timestamp":1753882824028,"version":"3.41.2"},"reference-count":18,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["SAGE Open Medical Case Reports"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:sec><jats:title>Background:<\/jats:title><jats:p> Hypergammaglobulinemic purpura of Waldenstr\u00f6m is an uncommon disease, which presents mostly in women on the lower extremities. It is sometimes associated with underlying immune dysregulation. Sj\u00f6gren syndrome is the most common association; however, rare occurrences of the self-resolving syndrome with lymphoma or myeloma have been reported. <\/jats:p><\/jats:sec><jats:sec><jats:title>Case Summary:<\/jats:title><jats:p> We describe an unusual and impressive presentation of hypergammaglobulinemic purpura of Waldenstr\u00f6m in an elderly female patient with myeloma. Notably, the patient did not have any concurrent connective tissue diseases. Despite her florid presentation, her hypergammaglobulinemic purpura of Waldenstr\u00f6m spontaneously resolved within a few days. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p> Hypergammaglobulinemic purpura of Waldenstr\u00f6m is a self-resolving but recurrent syndrome, which may be associated with autoimmune disorders or rarely myeloma. Early diagnosis of the syndrome may avoid unnecessary treatment interventions and should prompt screening for underlying diseases. <\/jats:p><\/jats:sec>","DOI":"10.1177\/2050313x221086321","type":"journal-article","created":{"date-parts":[[2022,3,22]],"date-time":"2022-03-22T09:17:36Z","timestamp":1647940656000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Hypergammaglobulinemic purpura of Waldenstr\u00f6m\u2014Unusual and impressive case in a patient with myeloma: A case report"],"prefix":"10.1177","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5960-3821","authenticated-orcid":false,"given":"Celina","family":"DeBiasio","sequence":"first","affiliation":[{"name":"Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janelle","family":"Cyr","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Department of Medicine, University of Ottawa, Ottawa, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephanie","family":"Petkiewicz","sequence":"additional","affiliation":[{"name":"Division of Anatomical Pathology, Department of Laboratory Medicine, University of Ottawa, Ottawa, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven J","family":"Glassman","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Department of Medicine, University of Ottawa, Ottawa, ON, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,3,22]]},"reference":[{"key":"bibr1-2050313X221086321","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2013.02.020"},{"key":"bibr2-2050313X221086321","doi-asserted-by":"publisher","DOI":"10.1111\/pde.14120"},{"key":"bibr3-2050313X221086321","doi-asserted-by":"publisher","DOI":"10.1159\/000207313"},{"key":"bibr4-2050313X221086321","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1957.00260090134019"},{"key":"bibr5-2050313X221086321","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1965.01600180071013"},{"key":"bibr6-2050313X221086321","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(86)90569-3"},{"key":"bibr7-2050313X221086321","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-003-0852-9"},{"key":"bibr8-2050313X221086321","doi-asserted-by":"publisher","DOI":"10.5070\/D300C6T853"},{"key":"bibr9-2050313X221086321","doi-asserted-by":"publisher","DOI":"10.4103\/0378-6323.77470"},{"issue":"4","key":"bibr10-2050313X221086321","first-page":"375","volume":"38","author":"Capra 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