{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T18:59:40Z","timestamp":1787165980152,"version":"build-2736575974"},"reference-count":6,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["SAGE Open Medical Case Reports"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:p>Epidermolysis bullosa acquisita is a rare autoimmune disease involving cutaneous blistering and scarring associated with collagen VII autoantibodies. Similarly, collagen VII autoantibodies are present in the majority of Crohn\u2019s disease patients and approximately a quarter of epidermolysis bullosa acquisita patients have coexisting Crohn\u2019s disease. Treatment options for epidermolysis bullosa acquisita are limited and are largely ineffective. Here, we describe a 36-year-old female with a history of Crohn\u2019s disease presenting with a 7-year history of severe blistering and scarring of acral surfaces. Diagnostic workup revealed subepidermal cleavage on skin biopsy and elevated serum collagen VII autoantibodies, indicative of epidermolysis bullosa acquisita. She was given ustekinumab for her coexisting Crohn\u2019s disease and, afterwards, her epidermolysis bullosa acquisita resolved as evidenced by a lack of new blisters or scarring. Further studies are required to evaluate the effects of ustekinumab on epidermolysis bullosa acquisita.<\/jats:p>","DOI":"10.1177\/2050313x221091600","type":"journal-article","created":{"date-parts":[[2022,4,15]],"date-time":"2022-04-15T02:48:11Z","timestamp":1649990891000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Epidermolysis bullosa acquisita treated with ustekinumab: A case report"],"prefix":"10.1177","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6790-220X","authenticated-orcid":false,"given":"Connor","family":"Prosty","sequence":"first","affiliation":[{"name":"Faculty of Medicine, McGill University, Montreal, QC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justina","family":"Guirguis","sequence":"additional","affiliation":[{"name":"Division of Dermatology, McGill University Health Centre, Montreal General Hospital, Montreal, QC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"May","family":"Chergui","sequence":"additional","affiliation":[{"name":"Department of Pathology, McGill University Health Centre, Montreal General Hospital, Montreal, QC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Waqqas","family":"Afif","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, McGill University Health Centre, Montreal General Hospital, Montreal, QC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Netchiporouk","sequence":"additional","affiliation":[{"name":"Division of Dermatology, McGill University Health Centre, Montreal General Hospital, Montreal, QC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,4,14]]},"reference":[{"key":"bibr1-2050313X221091600","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2018.00362"},{"key":"bibr2-2050313X221091600","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.2002.01772.x"},{"key":"bibr3-2050313X221091600","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.1903"},{"key":"bibr4-2050313X221091600","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kem330"},{"key":"bibr5-2050313X221091600","doi-asserted-by":"publisher","DOI":"10.1111\/ced.12114"},{"key":"bibr6-2050313X221091600","doi-asserted-by":"publisher","DOI":"10.1111\/j.1582-4934.2009.00959.x"}],"container-title":["SAGE Open Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2050313X221091600","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2050313X221091600","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2050313X221091600","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T13:06:38Z","timestamp":1740834398000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2050313X221091600"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1]]},"references-count":6,"alternative-id":["10.1177\/2050313X221091600"],"URL":"https:\/\/doi.org\/10.1177\/2050313x221091600","relation":{},"ISSN":["2050-313X","2050-313X"],"issn-type":[{"value":"2050-313X","type":"print"},{"value":"2050-313X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1]]},"article-number":"2050313X221091600"}}