{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T10:10:55Z","timestamp":1789726255739,"version":"4.0.1"},"reference-count":12,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["SAGE Open Medical Case Reports"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:p> Among drug-related complications, drug-related nephrotoxicity is the commonest. It is the cause for 7% of all drug-related toxicities among inpatients and accounts for 20% to 30% of acute renal failure. Acute interstitial nephritis is one of the drug-related adverse reactions and occurs due to a drug-related type 4 hypersensitivity reaction. In this case report, we reported acute interstitial nephritis that causes acute renal failure (acute kidney injury) in a patient taking Prothionamide therapy. This drug-related side effect had not been reported. In this case report, we report a patient who develops fatigability, rash, and intermittent fever after 14\u2009days of taking the drug Prothionamide. The main aims of this case report are to use it as a pharmacovigilance report for drug-producing companies and to consider a further study on this side effect. It is also an alert for clinicians to consider this side effect when patients develop acute interstitial nephritis while taking Prothionamide. <\/jats:p>","DOI":"10.1177\/2050313x221094076","type":"journal-article","created":{"date-parts":[[2022,5,18]],"date-time":"2022-05-18T23:34:35Z","timestamp":1652916875000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Acute interstitial nephritis with Prothionamide"],"prefix":"10.1177","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6665-7900","authenticated-orcid":false,"given":"Molla","family":"Asnake","sequence":"first","affiliation":[{"name":"School of Medicine, College of Health Sciences, Mizan-Tepi University, Mizan Teferi, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andualem","family":"Henock","sequence":"additional","affiliation":[{"name":"School of Public Health, College of Health Sciences, Mizan-Tepi University, Mizan Teferi, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Menigistu","family":"Abayneh","sequence":"additional","affiliation":[{"name":"Department of Medical Laboratory Technology, College of Health Sciences, Mizan-Tepi University, Mizan Teferi, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shimelis","family":"Getu","sequence":"additional","affiliation":[{"name":"School of Medicine, College of Health Sciences, Wolkite University, Wolkite, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shewangizaw","family":"Hailemariam","sequence":"additional","affiliation":[{"name":"Department of Midwifery, College of Health Sciences, Mizan-Tepi University, Mizan Teferi, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Biruk","family":"Endalkachew","sequence":"additional","affiliation":[{"name":"Department of Biomedical Science, College of Health Sciences, Mizan-Tepi University, Mizan Teferi, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dessalegn","family":"Zerihun","sequence":"additional","affiliation":[{"name":"USAID Eliminate TB Project, KNCV Tuberculosis Foundation, Hawassa, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,5,13]]},"reference":[{"key":"bibr1-2050313X221094076","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)70238-5"},{"key":"bibr2-2050313X221094076","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-139X.1996.tb00304.x"},{"key":"bibr3-2050313X221094076","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ki.5002224"},{"key":"bibr4-2050313X221094076","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(99)00113-8"},{"key":"bibr5-2050313X221094076","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2017.02358"},{"key":"bibr6-2050313X221094076","doi-asserted-by":"publisher","DOI":"10.1016\/j.tube.2015.09.007"},{"key":"bibr7-2050313X221094076","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(10)70139-0"},{"key":"bibr8-2050313X221094076","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20062100"},{"key":"bibr9-2050313X221094076","doi-asserted-by":"publisher","DOI":"10.1086\/374225"},{"key":"bibr10-2050313X221094076","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198403013100905"},{"key":"bibr11-2050313X221094076","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfh485"},{"key":"bibr12-2050313X221094076","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ki.5002776"}],"container-title":["SAGE Open Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2050313X221094076","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2050313X221094076","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2050313X221094076","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,2]],"date-time":"2025-03-02T15:57:45Z","timestamp":1740931065000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2050313X221094076"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1]]},"references-count":12,"alternative-id":["10.1177\/2050313X221094076"],"URL":"https:\/\/doi.org\/10.1177\/2050313x221094076","relation":{},"ISSN":["2050-313X","2050-313X"],"issn-type":[{"value":"2050-313X","type":"print"},{"value":"2050-313X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1]]},"article-number":"2050313X221094076"}}