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Duplication of 17q12 is a rare genetic condition associated with variable characteristics from clinically asymptomatic to intellectual disabilities, seizures, and behavioral problems. The variability in phenotype is primarily due to variable expressivity and incomplete penetrance. Diagnosis is mostly established by chromosomal microarray. Treatment involves a multidisciplinary approach. We present a case of a 43-year-old female who initially presented with hyperphagia and was eventually diagnosed with bulimia nervosa, anxiety, mood disorder, and personality disorder. Additional research is required to better understand the impact of 17q12 duplication syndrome on the development of bulimia nervosa since its pathogenesis has not been adequately described in the current literature. <\/jats:p>","DOI":"10.1177\/2050313x241233184","type":"journal-article","created":{"date-parts":[[2024,2,19]],"date-time":"2024-02-19T11:20:03Z","timestamp":1708341603000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Complex neuropsychiatric presentation of 17q12 duplication syndrome: A case report"],"prefix":"10.1177","volume":"12","author":[{"given":"Soumitra","family":"Das","sequence":"first","affiliation":[{"name":"Department of Psychiatry, Western Health, Footscray, VIC, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lochana","family":"Samarasinghe","sequence":"additional","affiliation":[{"name":"Base Hospital Nikaweratiya, Nikaweratiya, 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