{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T21:48:30Z","timestamp":1790891310309,"version":"4.1.0"},"reference-count":12,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["SAGE Open Medical Case Reports"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:p> A gastric ulcer is a tear in the stomach lining that manifests as abdominal pain, nausea, vomiting, and weight loss. Its occurrence is lesser in children as compared to adults and its incidence in children ranges between 2% and 8%. Helicobacter pylori and nonsteroidal anti-inflammatory drugs are the most common causes of gastric ulcers. In our case, we report a 2.5-month-old male who presented with severe pallor, hematemesis, and melena with normal weight gain. The patient\u2019s mother was infected with COVID-19 a month ago and recovered within 5 days but kept using aspirin and nonsteroidal anti-inflammatory drugs for a month during breastfeeding. An upper gastrointestinal endoscopy revealed a gastric ulcer and the Helicobacter pylori antigen was positive in the biopsy. A COVID-19 infection was detected later in the patient. The patient was administered proton pump inhibitor, clarithromycin, and amoxicillin for Helicobacter pylori antigen and symptomatic treatment for COVID-19. This case report shows that a stomach ulcer can appear in infancy, but opportune interventions such as timely diagnosis and treatment can solve the problem. It also marks the pathophysiological connection between Helicobacter pylori and gastric ulcer. <\/jats:p>","DOI":"10.1177\/2050313x241242932","type":"journal-article","created":{"date-parts":[[2024,3,29]],"date-time":"2024-03-29T11:11:38Z","timestamp":1711710698000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["A case report of a gastric ulcer in a 2.5-month-old infant in Syria: <i>Helicobacter pylori<\/i> and Aspirin as possible causes"],"prefix":"10.1177","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9289-0674","authenticated-orcid":false,"given":"Nafiza","family":"Martini","sequence":"first","affiliation":[{"name":"Faculty of Medicine, Damascus University, Damascus, Syrian Arab Republic"},{"name":"Stemosis for Scientific Research, Damascus, Syrian Arab Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maha","family":"Al haj Kaddour","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Damascus University, Damascus, Syrian Arab Republic"},{"name":"Stemosis for Scientific Research, Damascus, Syrian Arab Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6199-2494","authenticated-orcid":false,"given":"Mouna","family":"Baddoura","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Damascus University, Damascus, Syrian Arab Republic"},{"name":"Stemosis for Scientific Research, Damascus, Syrian Arab Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mulham","family":"Jarjanazi","sequence":"additional","affiliation":[{"name":"Aleppo University Hospital, Aleppo, Syrian Arab Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaber","family":"Mahmoud","sequence":"additional","affiliation":[{"name":"Stemosis for Scientific Research, Damascus, Syrian Arab Republic"},{"name":"Pediatric University Hospital, Damascus University, Damascus, Syrian Arab Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,3,29]]},"reference":[{"key":"bibr1-2050313X241242932","volume-title":"StatPearls","author":"Woolf A","year":"2024"},{"key":"bibr2-2050313X241242932","doi-asserted-by":"publisher","DOI":"10.1542\/pir.16.7.257"},{"key":"bibr3-2050313X241242932","doi-asserted-by":"publisher","DOI":"10.1542\/pir.2017-0234"},{"key":"bibr4-2050313X241242932","doi-asserted-by":"publisher","DOI":"10.1159\/000331517"},{"key":"bibr5-2050313X241242932","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)32404-7"},{"key":"bibr6-2050313X241242932","doi-asserted-by":"publisher","DOI":"10.1542\/pir.22-10-349"},{"key":"bibr7-2050313X241242932","doi-asserted-by":"publisher","DOI":"10.1080\/20469047.2018.1490100"},{"key":"bibr8-2050313X241242932","doi-asserted-by":"publisher","DOI":"10.1016\/S0188-4409(00)00099-0"},{"key":"bibr9-2050313X241242932","doi-asserted-by":"publisher","DOI":"10.1111\/j.1523-5378.2011.00882.x"},{"key":"bibr10-2050313X241242932","doi-asserted-by":"publisher","DOI":"10.1111\/jgh.14090"},{"key":"bibr11-2050313X241242932","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0b013e31828a4b54"},{"key":"bibr12-2050313X241242932","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinre.2020.07.025"}],"container-title":["SAGE Open Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2050313X241242932","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2050313X241242932","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2050313X241242932","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:22:38Z","timestamp":1740788558000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2050313X241242932"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":12,"alternative-id":["10.1177\/2050313X241242932"],"URL":"https:\/\/doi.org\/10.1177\/2050313x241242932","relation":{},"ISSN":["2050-313X","2050-313X"],"issn-type":[{"value":"2050-313X","type":"print"},{"value":"2050-313X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1]]},"article-number":"2050313X241242932"}}