{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T20:11:11Z","timestamp":1791231071250,"version":"4.1.0"},"reference-count":24,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["SAGE Open Medical Case Reports"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:p> This report presents a rare case of bronchogenic adenocarcinoma with initial metastasis in the external auditory canal. The patient, a 64-year-old man with a history of bladder urothelial carcinoma, initially presented with a persistent right otitis externa. Otoscopic examination revealed a mass obstructing the right external auditory canal. The temporal bone computed tomography scan revealed a mass that completely obstructed the right external auditory canal and extended into the middle ear. A biopsy showed a poorly differentiated adenocarcinoma of bronchogenic origin, confirmed by positive immunohistochemical staining for cytokeratin 7 and Thyroid transcription factor-1. Further imaging revealed a large tumor mass in the lung involving the mediastinum and parenchyma, along with carcinomatous lymphangitis and cerebral metastasis. Histopathological examination of the primary lung tumor confirmed a poorly differentiated adenocarcinoma with similar features to the metastasis in the external auditory canal. The tumor was staged as T4N2M1c, and the patient underwent local external-beam radiation therapy with chemotherapy. <\/jats:p>","DOI":"10.1177\/2050313x241258155","type":"journal-article","created":{"date-parts":[[2024,5,31]],"date-time":"2024-05-31T10:50:36Z","timestamp":1717152636000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["External auditory canal metastasis revealing bronchogenic carcinoma: A case report and literature review"],"prefix":"10.1177","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5433-6808","authenticated-orcid":false,"given":"Sirine","family":"Ayadi","sequence":"first","affiliation":[{"name":"ENT Department and Research Laboratory LR23ES01, Habib Bourguiba University Hospital, University of Sfax, Sfax, Tunisia"},{"name":"Faculty of Medicine of Sfax, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omar","family":"Walha","sequence":"additional","affiliation":[{"name":"ENT Department and Research Laboratory LR23ES01, Habib Bourguiba University Hospital, University of Sfax, Sfax, Tunisia"},{"name":"Faculty of Medicine of Sfax, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rania","family":"Kharrat","sequence":"additional","affiliation":[{"name":"ENT Department and Research Laboratory LR23ES01, Habib Bourguiba University Hospital, University of Sfax, Sfax, Tunisia"},{"name":"Faculty of Medicine of Sfax, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9296-762X","authenticated-orcid":false,"given":"Mariem","family":"Ben Ayed","sequence":"additional","affiliation":[{"name":"ENT Department and Research Laboratory LR23ES01, Habib Bourguiba University Hospital, University of Sfax, Sfax, Tunisia"},{"name":"Faculty of Medicine of Sfax, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boutheina","family":"Hammami","sequence":"additional","affiliation":[{"name":"ENT Department and Research Laboratory LR23ES01, Habib Bourguiba University Hospital, University of Sfax, Sfax, Tunisia"},{"name":"Faculty of Medicine of Sfax, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed Amine","family":"Chaabouni","sequence":"additional","affiliation":[{"name":"ENT Department and Research Laboratory LR23ES01, Habib Bourguiba University Hospital, University of Sfax, Sfax, Tunisia"},{"name":"Faculty of Medicine of Sfax, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilhem","family":"Charfeddine","sequence":"additional","affiliation":[{"name":"ENT Department and Research Laboratory LR23ES01, Habib Bourguiba University Hospital, University of Sfax, Sfax, Tunisia"},{"name":"Faculty of Medicine of Sfax, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,5,31]]},"reference":[{"key":"bibr1-2050313X241258155","doi-asserted-by":"publisher","DOI":"10.1016\/j.anorl.2012.08.003"},{"key":"bibr2-2050313X241258155","doi-asserted-by":"publisher","DOI":"10.1177\/000348941312200606"},{"key":"bibr3-2050313X241258155","doi-asserted-by":"publisher","DOI":"10.5334\/jbr-btr.853"},{"key":"bibr4-2050313X241258155","doi-asserted-by":"publisher","DOI":"10.1177\/014556131209101107"},{"key":"bibr5-2050313X241258155","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccm.2019.10.001"},{"key":"bibr6-2050313X241258155","doi-asserted-by":"publisher","DOI":"10.1016\/j.lungcan.2014.07.020"},{"key":"bibr7-2050313X241258155","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12041429"},{"key":"bibr8-2050313X241258155","doi-asserted-by":"publisher","DOI":"10.1177\/014556130508400113"},{"key":"bibr9-2050313X241258155","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215108002867"},{"key":"bibr10-2050313X241258155","volume":"2018","author":"James A","year":"2018","journal-title":"BMJ Case Rep"},{"key":"bibr11-2050313X241258155","first-page":"270","volume":"116","author":"Huseynov J","year":"2019","journal-title":"Dtsch Arztebl Int"},{"key":"bibr12-2050313X241258155","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100128208"},{"issue":"17","key":"bibr13-2050313X241258155","first-page":"85","volume":"1","author":"Baraka BA","year":"2015","journal-title":"Gulf J Oncolog"},{"key":"bibr14-2050313X241258155","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2005.07.002"},{"issue":"8","key":"bibr15-2050313X241258155","first-page":"1059","volume":"2","author":"Rangachari V","year":"2015","journal-title":"Austin J Otolaryngol"},{"key":"bibr16-2050313X241258155","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2009.07.017"},{"key":"bibr17-2050313X241258155","doi-asserted-by":"publisher","DOI":"10.1111\/ans.15657"},{"key":"bibr18-2050313X241258155","doi-asserted-by":"publisher","DOI":"10.3816\/CGC.2007.n.015"},{"key":"bibr19-2050313X241258155","doi-asserted-by":"publisher","DOI":"10.1016\/j.eucr.2022.102141"},{"key":"bibr20-2050313X241258155","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v13.i47.6436"},{"issue":"7","key":"bibr21-2050313X241258155","first-page":"1416","volume":"6","author":"Zhao R","year":"2013","journal-title":"Int J Clin Exp Pathol"},{"key":"bibr22-2050313X241258155","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinimag.2020.11.029"},{"key":"bibr23-2050313X241258155","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21763"},{"key":"bibr24-2050313X241258155","doi-asserted-by":"publisher","DOI":"10.3892\/ol.2017.6511"}],"container-title":["SAGE Open Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2050313X241258155","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2050313X241258155","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2050313X241258155","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,3]],"date-time":"2025-03-03T08:17:49Z","timestamp":1740989869000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2050313X241258155"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":24,"alternative-id":["10.1177\/2050313X241258155"],"URL":"https:\/\/doi.org\/10.1177\/2050313x241258155","relation":{},"ISSN":["2050-313X","2050-313X"],"issn-type":[{"value":"2050-313X","type":"print"},{"value":"2050-313X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1]]},"article-number":"2050313X241258155"}}