{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T11:44:39Z","timestamp":1784547879080,"version":"3.55.0"},"reference-count":22,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["SAGE Open Medical Case Reports"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:p> Primary lymphoepithelial carcinoma of the salivary glands is an exceptional oncological condition that predominantly emerges within the parotid gland. A significant prevalence of lymphoepithelial carcinoma has been reported in the Inuit population, along with an associated positive serology for Epstein-Barr virus in these endemic regions. In this paper, we present a case of primary lymphoepithelial carcinoma of the parotid gland in a 68-year-old female patient with a history of diabetes and hypertension residing in a non-endemic area. Histology plays a critical role in the definitive diagnosis, and confirming the primary origin of lymphoepithelial carcinoma after ruling out metastasis from undifferentiated nasopharyngeal carcinoma. The mainstay of treatment is a combination of surgical resection and adjuvant radiotherapy. Inoperable forms are typically managed with chemoradiotherapy. <\/jats:p>","DOI":"10.1177\/2050313x241260210","type":"journal-article","created":{"date-parts":[[2024,6,12]],"date-time":"2024-06-12T07:57:58Z","timestamp":1718179078000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Lymphoepithelial carcinoma of the parotid gland"],"prefix":"10.1177","volume":"12","author":[{"given":"Souha","family":"Kallel","sequence":"first","affiliation":[{"name":"ENT Department and Research Laboratory LR23ES01, Habib Bourguiba University Hospital, University of Sfax, Sfax, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5433-6808","authenticated-orcid":false,"given":"Sirine","family":"Ayadi","sequence":"additional","affiliation":[{"name":"ENT Department and Research Laboratory LR23ES01, Habib Bourguiba University Hospital, University of Sfax, Sfax, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noura","family":"Salem","sequence":"additional","affiliation":[{"name":"ENT Department and Research Laboratory LR23ES01, Habib Bourguiba University Hospital, University of Sfax, Sfax, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mouna","family":"Zghal","sequence":"additional","affiliation":[{"name":"Department of Pathology and Research Laboratory LR18SP10, Habib Bourguiba University Hospital, University of Sfax, Sfax, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9296-762X","authenticated-orcid":false,"given":"Ben Ayed","family":"Mariem","sequence":"additional","affiliation":[{"name":"ENT Department and Research Laboratory LR23ES01, Habib Bourguiba University Hospital, University of Sfax, Sfax, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lobna","family":"Ayedi","sequence":"additional","affiliation":[{"name":"Department of Pathology and Research Laboratory LR18SP10, Habib Bourguiba University Hospital, University of Sfax, Sfax, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malek","family":"Mnejja","sequence":"additional","affiliation":[{"name":"ENT Department and Research Laboratory LR23ES01, Habib Bourguiba University Hospital, University of Sfax, Sfax, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tahya","family":"Boudawara","sequence":"additional","affiliation":[{"name":"Department of Pathology and Research Laboratory LR18SP10, Habib Bourguiba University Hospital, University of Sfax, Sfax, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilhem","family":"Charfeddine","sequence":"additional","affiliation":[{"name":"ENT Department and Research Laboratory LR23ES01, Habib Bourguiba University Hospital, University of Sfax, Sfax, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,6,12]]},"reference":[{"key":"bibr1-2050313X241260210","doi-asserted-by":"publisher","DOI":"10.5858\/2008-132-278-LCOTPG"},{"key":"bibr2-2050313X241260210","doi-asserted-by":"publisher","DOI":"10.1016\/j.path.2020.09.009"},{"key":"bibr3-2050313X241260210","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2006.12.012"},{"key":"bibr4-2050313X241260210","doi-asserted-by":"publisher","DOI":"10.4103\/jcrt.JCRT_280_17"},{"key":"bibr5-2050313X241260210","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2017.05.014"},{"key":"bibr6-2050313X241260210","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.161.2.3763909"},{"key":"bibr7-2050313X241260210","unstructured":"TNM-Classification-of-Malignant-Tumours-8th-edition.pdf. Disponible sur, http:\/\/mom.gov.az\/resources\/content_files\/ebook\/TNM-Classification-of-Malignant-Tumours-8th-edition.pdf."},{"key":"bibr8-2050313X241260210","doi-asserted-by":"publisher","DOI":"10.1053\/j.semdp.2014.12.004"},{"key":"bibr9-2050313X241260210","doi-asserted-by":"publisher","DOI":"10.1002\/hed.27083"},{"key":"bibr10-2050313X241260210","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2009.10.016"},{"key":"bibr11-2050313X241260210","doi-asserted-by":"publisher","DOI":"10.1177\/03000605221148895"},{"key":"bibr12-2050313X241260210","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2015.10.019"},{"key":"bibr13-2050313X241260210","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(91)90141-Y"},{"key":"bibr14-2050313X241260210","doi-asserted-by":"publisher","DOI":"10.1007\/s00795-021-00295-5"},{"key":"bibr15-2050313X241260210","doi-asserted-by":"publisher","DOI":"10.1007\/s12105-020-01172-w"},{"key":"bibr16-2050313X241260210","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.11002"},{"issue":"3","key":"bibr17-2050313X241260210","first-page":"1004","volume":"7","author":"Zhang G","year":"2014","journal-title":"Int J Clin Exp Pathol"},{"key":"bibr18-2050313X241260210","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2559.1997.5830814.x"},{"key":"bibr19-2050313X241260210","doi-asserted-by":"publisher","DOI":"10.1186\/1746-1596-8-115"},{"key":"bibr20-2050313X241260210","doi-asserted-by":"publisher","DOI":"10.1007\/s12032-014-0957-9"},{"issue":"9","key":"bibr21-2050313X241260210","first-page":"1305","volume":"36","author":"Ma H","year":"2014","journal-title":"Head Neck"},{"key":"bibr22-2050313X241260210","doi-asserted-by":"publisher","DOI":"10.1177\/030089160108700103"}],"container-title":["SAGE Open Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2050313X241260210","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2050313X241260210","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2050313X241260210","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,3]],"date-time":"2025-03-03T06:42:40Z","timestamp":1740984160000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2050313X241260210"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":22,"alternative-id":["10.1177\/2050313X241260210"],"URL":"https:\/\/doi.org\/10.1177\/2050313x241260210","relation":{},"ISSN":["2050-313X","2050-313X"],"issn-type":[{"value":"2050-313X","type":"print"},{"value":"2050-313X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1]]},"article-number":"2050313X241260210"}}