{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T13:40:12Z","timestamp":1753882812537,"version":"3.41.2"},"reference-count":16,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["SAGE Open Medical Case Reports"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:p> In extracorporeal circulation, inflammatory mediators are eliminated through inflammatory cytokine adsorption. By interacting with inflammatory cytokines and removing them from the bloodstream, the adsorber\u2019s adsorbent lowers levels of inflammatory mediators and the inflammatory response. We present the case of a 67-year-old Chinese man diagnosed with sepsis due to a bloodstream infection from a catheter. We promptly utilized a cytokine adsorption column in conjunction with continuous veno-venous hemodiafiltration (CVVHDF), resulting in a decrease in interleukin-6 levels and complete removal of bascteria from the bloodstream. A critical turning point in illness management is reached as the levels of inflammatory cytokines drop and the dosage of patients\u2019 vasoactive medications improves significantly. In hemodialysis patients with secondary septic shock in the context of catheter-associated bacteremia, the combination of CVVHDF with cytokine adsorption therapy in hemodialysis may be clinically useful and improve or accelerate the patient\u2019s improvement. <\/jats:p>","DOI":"10.1177\/2050313x241272670","type":"journal-article","created":{"date-parts":[[2024,8,22]],"date-time":"2024-08-22T18:09:42Z","timestamp":1724350182000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["CVVHDF combined with cytokine adsorption column ameliorates severe catheter-related bloodstream infection in a hemodialysis patient"],"prefix":"10.1177","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1755-2894","authenticated-orcid":false,"given":"Yingjing","family":"Shen","sequence":"first","affiliation":[{"name":"Department of Nephrology, Shanghai Tianyou Hospital, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,8,22]]},"reference":[{"key":"bibr1-2050313X241272670","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2019.01.017"},{"key":"bibr2-2050313X241272670","volume":"4","author":"Almeida BM","year":"2022","journal-title":"Cochrane Database Syst Rev"},{"key":"bibr3-2050313X241272670","volume":"15","author":"Abbasi SH","year":"2020","journal-title":"PLoS One"},{"key":"bibr4-2050313X241272670","doi-asserted-by":"crossref","first-page":"3145","DOI":"10.2147\/IDR.S409400","volume":"16","author":"Weldetensae MK","year":"2023","journal-title":"Infect Drug Resist"},{"key":"bibr5-2050313X241272670","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1097\/MAT.0000000000001382","volume":"67","author":"Abdul SS","year":"2021","journal-title":"Asaio J"},{"key":"bibr6-2050313X241272670","doi-asserted-by":"publisher","DOI":"10.3390\/ijms221910238"},{"key":"bibr7-2050313X241272670","doi-asserted-by":"crossref","first-page":"628302","DOI":"10.3389\/fmed.2021.628302","volume":"8","author":"Jarczak D","year":"2021","journal-title":"Front Med (Lausanne)"},{"key":"bibr8-2050313X241272670","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-023-04391-z"},{"key":"bibr9-2050313X241272670","doi-asserted-by":"publisher","DOI":"10.1159\/000500013"},{"key":"bibr10-2050313X241272670","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2021.718049"},{"key":"bibr11-2050313X241272670","doi-asserted-by":"crossref","first-page":"1334","DOI":"10.1007\/s00134-021-06512-0","volume":"47","author":"Wendel GP","year":"2021","journal-title":"Intens Care Med"},{"key":"bibr12-2050313X241272670","doi-asserted-by":"publisher","DOI":"10.1111\/aas.14115"},{"key":"bibr13-2050313X241272670","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-89965-z"},{"key":"bibr14-2050313X241272670","doi-asserted-by":"publisher","DOI":"10.1159\/000524973"},{"key":"bibr15-2050313X241272670","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22168882"},{"key":"bibr16-2050313X241272670","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-023-04492-9"}],"container-title":["SAGE Open Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2050313X241272670","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2050313X241272670","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2050313X241272670","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T11:42:21Z","timestamp":1740829341000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2050313X241272670"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":16,"alternative-id":["10.1177\/2050313X241272670"],"URL":"https:\/\/doi.org\/10.1177\/2050313x241272670","relation":{},"ISSN":["2050-313X","2050-313X"],"issn-type":[{"type":"print","value":"2050-313X"},{"type":"electronic","value":"2050-313X"}],"subject":[],"published":{"date-parts":[[2024,1]]},"article-number":"2050313X241272670"}}